Various water column variables, including salinity, dissolved inorganic nutrients, pH, total alkalinity, dissolved inorganic carbon, rwere measured in samples collected using a Niskin-bottle rosette at selected depths from sites offshore of California and Oregon from October to November 2019 during NOAA cruise RL-19-05 on the R/V Reuben Lasker (USGS field activity 2019-672-FA). CTD (Conductivity Temperature Depth) data were also collected at each depth that a Niskin-bottle sample was collected and are presented along with the water sample data.