Publications
Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).
Filter Total Items: 683
Potential toxicity of complex mixtures in surface waters from a nationwide survey of United States streams: Identifying in vitro bioactivities and causative chemicals
While chemical analysis of contaminant mixtures remains an essential component of environmental monitoring, bioactivity-based assessments using in vitro systems increasingly play a role in the detection of biological effects. Historically, in vitro assessments focused on a few biological pathways, e.g., aryl hydrocarbon receptor (AhR) or estrogen receptor (ER) activities. High-throughput screening
Authors
Brett R. Blackwell, Gerald T. Ankley, Paul M. Bradley, Keith A. Houck, Sergei S. Makarov, Alexander V. Medvedev, Joe Swintek, Daniel L. Villeneuve
Absence of PCB hot spot effect in walleye Sander vitreus from lower Green Bay of Lake Michigan
Under certain conditions, polychlorinated biphenyl (PCB) concentration in individuals of one sex of an adult fish population may exceed that of the other sex by more than a factor of two. This phenomenon, known as the PCB hot spot effect, has been postulated to be contingent upon the following two conditions: (1) presence of a PCB hot spot in the bottom sediments of the aquatic ecosystem such th
Authors
Charles P. Madenjian, Daniel J. Dembkowski, Daniel A. Isermann, Stuart A. Batterman, Sergei C. Chernyak, Stewart F. Cogswell, Mark E. Holey
Short-term effects of ambient air pollution and cardiovascular events in Shiraz, Iran, 2009 to 2015
Air pollution and dust storms are associated with increased cardiovascular hospital admissions. The aim of this study was to investigate the association between short-term exposure to ambient air pollutants and CVD (cardiovascular disease) events in a long-term observational period. The study included the events of cardiovascular diseases (namely coronary artery disease, ischemic heart disease, my
Authors
Zahra Soleimani, Ali Darvishi Boloorani, Reza Khalifeh, Dale W. Griffin, Alireza Mesdaghinia
Multiple approaches to surface water quality assessment provide insight for small streams experiencing oil and natural gas development
Historic, current, and future oil and natural gas development can affect water quality in streams flowing through developed areas. We compared small stream drainages in a semi-arid landscape with varying amounts of disturbance from oil and natural gas development to examine potential effects of this development on surface water quality. We used physical, chemical, and biological approaches to asse
Authors
Annika W. Walters, Carlin Girard, Richard H. Walker, Aida Farag, David Alvarez
UZIG research: Measurement and characterization of unsaturated zone processes under wide-ranging climates and changing conditions
Unsaturated zone properties and processes are central to understanding the interacting effects of land-use change, contamination, and hydroclimate on our ability to grow food, sustain clean water supplies, and minimize loss of life and property. Advances in unsaturated zone science are being achieved through collaborations across traditional boundaries where information from biological, physical,
Authors
Jared J. Trost, Benjamin B. Mirus, Kimberlie Perkins, Wesley R. Henson, John R. Nimmo, Rafael Munoz-Carpena
Use of blood clotting assays to assess potential anticoagulant rodenticide exposure and effects in free-ranging birds of prey
Non-target wildlife, particularly birds of prey, are widely exposed to and acutely poisoned by anticoagulant rodenticides (ARs). An unresolved issue surrounding such exposure, however, is the potential for sublethal effects. In particular, the consequences of AR exposure and resulting coagulopathy on health and survival of unintentionally exposed animals, which often encounter a multitude of anthr
Authors
Sofi Hindmarch, Barnett A. Rattner, John E. Elliott
Polychlorinated biphenyl tissue‐concentration thresholds for survival, growth, and reproduction in fish
Polychlorinated biphenyls (PCBs) have left a legacy of environmental contamination. Even though they were banned from production and active use in the 1970s, they persist in the environment and still have the potential to impact aquatic life. Our objective was to identify data from controlled laboratory studies of PCB‐related adverse effects in fish and to conduct a meta‐analysis on mortality, gro
Authors
Jason P. Berninger, Donald E. Tillitt
Sex‐specific responses in neuroanatomy of hatchling American kestrels in response to embryonic exposure to the flame retardants bis(2‐ethylhexyl)‐2,3,4,5‐tetrabromophthalate and 2‐ethylhexyl‐2,3,4,5‐tetrabromobenzoate
Bis(2‐ethylhexyl)‐2,3,4,5‐tetrabromophthalate (BEH‐TEBP) and 2‐ethylhexyl‐2,3,4,5‐tetrabromobenzoate (EH‐TBB), flame retardant components of FireMaster 550® and 600® have been detected in tissues of wild birds. To address the paucity of information regarding potential impacts of flame retardants on the brain, brain volume regions of hatchling American kestrels (Falco sparverius) were evaluated fol
Authors
Mélanie F. Guigueno, Natalie K. Karouna-Renier, Paula F. P. Henry, Lisa E. Peters, Vince P. Palace, Robert J. Letcher, Kim J. Fernie
Characterizing toxicity of metal‐contaminated sediments from the Upper Columbia River, Washington, USA, to benthic invertebrates
Sediments from the Upper Columbia River, Washington, USA, are contaminated with metals from smelting operations. We conducted short‐term and long‐term tests with the midge Chironomus dilutus and the amphipod Hyalella azteca and short‐term tests with the freshwater mussel Lampsilis siliquoidea with 54 sediments from the Upper Columbia River to characterize thresholds for toxicity of metals to benth
Authors
John M. Besser, Jeffery Steevens, James L. Kunz, William G. Brumbaugh, Christopher G. Ingersoll, Stephen E. Cox, Christopher A. Mebane, Laurie S. Balistrieri, Jesse A. Sinclair, Donald D. MacDonald
Mixed-chemical exposure and predicted effects potential in wadeable southeastern USA streams
Complex chemical mixtures have been widely reported in larger streams but relatively little work has been done to characterize them and assess their potential effects in headwaterstreams. In 2014, the United States Geological Survey (USGS) sampled 54 Piedmont streams over ten weeks and measured 475 unique organic compounds using five analytical methods. Maximum and median exposure conditions were
Authors
Paul M. Bradley, Celeste A. Journey, Jason P. Berninger, Daniel T. Button, Jimmy M. Clark, Steven R. Corsi, Laura A. DeCicco, Kristina G. Hopkins, Bradley J. Huffman, Naomi Nakagaki, Julia E. Norman, Lisa H. Nowell, Sharon L. Qi, Peter C. Van Metre, Ian R. Waite
A diverse suite of pharmaceuticals contaminates stream and riparian food webs
A multitude of biologically active pharmaceuticals contaminate surface waters globally, yet their presence in aquatic food webs remain largely unknown. Here, we show that over 60 pharmaceutical compounds can be detected in aquatic invertebrates and riparian spiders in six streams near Melbourne, Australia. Similar concentrations in aquatic invertebrate larvae and riparian predators suggest direct
Authors
Erinn K. Richmond, Emma J. Rosi, David M. Walters, Jerker Fikk, Stephen K. Hamilton, Tomas Brodin, Anna Sundelin, Michael R. Grace
Hydrogeochemical controls on brook trout spawning habitats in a coastal stream
Brook trout (Salvelinus fontinalis) spawn in fall and overwintering egg development can benefit from stable, relatively warm temperatures in groundwater-seepage zones. However, eggs are also sensitive to dissolved oxygen concentration, which may be reduced in discharging groundwater (i.e., seepage). We investigated a 2 km reach of the coastal Quashnet River in Cape Cod, Massachusetts, USA, to rela
Authors
Martin A. Briggs, Judson W. Harvey, Stephen T. Hurley, Donald O. Rosenberry, Timothy D. McCobb, Dale D. Werkema, John W. Lane