USGS National Wildlife Health Center laboratory technician preparing avian samples for avian influenza testing.
Hon Ip
Hon Ip is a Diagnostic and Research Virologist at the National Wildlife Health Center.
As a Diagnostic and Research Virologist, I am interested in the emergence and spread of novel, introduced, and endemic viral diseases of wildlife. For example, through the National Wildlife Health Center’s long-standing program to investigate wildlife mortality events in the United States, our Diagnostic Virology Laboratory was first to detect introductions of West Nile Virus (in 1999) and Highly Pathogenic Avian Influenza H5N8 (in 2014). Both of these introductions resulted in large-scale monitoring efforts that provided real-time and actionable intelligence to state and federal partners for disease response. We have also investigated periodic recurrence of Newcastle Disease in cormorants, geographic expansion of Eurasian collared doves and associated spread of pigeon paramyxovirus, and applied phylogenetic approaches to understand the diversity and transmission of viral diseases on the landscape. Since 2008 we have been studying viruses in North American bats, including coronaviruses. Following the recent emergence of COVID-19, this work provides a highly relevant framework for investigating possible impacts of the SARS-CoV-2 virus on native, North American bat species, and for more broadly characterizing the diversity of coronaviruses in North American wildlife.
Professional Experience
Diagnostic and Research Virologist at the National Wildlife Health Center
Education and Certifications
Ph. D. Molecular Parasitology. The Rockefeller University, New York, NY.
M. Sc. Microbiology and Parasitology. University of Toronto, Ontario, Canada.
B. Sc. Microbiology and Parasitology. University of Toronto, Ontario, Canada.
Affiliations and Memberships*
Honorary Associate Fellow. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison.
Adjunct Assistant Professor. Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison.
Science and Products
Investigating coronaviruses and white-nose syndrome fungus in free-ranging North American bats
Avian Influenza Surveillance
Tracking Bats and Coronaviruses
Diagnostic Virology Laboratory (DVL)
The USGS National Wildlife Health Center's Diagnostic Virology Laboratory (DVL) detects existing and identifies emerging pathogens of wildlife.
Avian Influenza
Vector-Borne Diseases
Human Influenza Virus Infects Sea Otters
Avian disease screening of translocated sage grouse captured in Montana, USA
Little Brown Bats (Myotis lucifugus) weights and Ct values for SARS-CoV-2 Infection challenge
Epidemiologic and diagnostic data from two red foxes (Vulpes vulpes) and one fisher (Pekania pennanti) with highly pathogenic avian influenza H5N1 submitted to the USGS National Wildlife Health Center in 2022
Raw MinION FASTQ datafiles corresponding to the paper “A comparison of avian influenza virus whole genome sequencing approaches using nanopore technology”
Viral loads, histology, and adverse events in transgenic mice after passive transfer of serum from black-footed ferrets (Mustela nigripes) used to assess the anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate
Data from the article “An opportunistic survey reveals an unexpected coronavirus diversity hotspot in North America”
Data set on reticuloendotheliosis in Hawaiian birds
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
Data from pathology of Lagovirus europaeus GI.2/RHDV2/b (rabbit hemorrhagic disease virus 2) in native North American lagomorphs
Avian Influenza Virus Test Results from Active Surveillance of North American Wild Birds Collected by Department of Interior from 2006-2011
Natural infections with Pigeon Paramyxovirus-1: Pathologic changes in Eurasian collared-doves (Streptopelia decaocto) and rock pigeons (Columba livia) in the USA: Data
USGS National Wildlife Health Center laboratory technician preparing avian samples for avian influenza testing.
Samples awaiting testing in the National Wildlife Health Center Diagnostic Virology Laboratory.
Samples awaiting testing in the National Wildlife Health Center Diagnostic Virology Laboratory.
Genotypic clustering of H5N1 avian Influenza viruses in North America evaluated by ordination analysis
Antibody response of endangered riparian brush rabbits to vaccination against rabbit hemorrhagic disease virus 2
Little brown bats (Myotis lucifugus) are resistant to SARS-CoV-2 infection
Highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b infections in wild terrestrial mammals, United States, 2022
H5N1 highly pathogenic avian influenza clade 2.3.4.4b in wild and domestic birds: Introductions into the United States and reassortments, December 2021–April 2022
Successful detection of Delta and Omicron Variants of SARS-CoV-2 by veterinary diagnostic laboratory participants in an interlaboratory comparison exercise
Comparison of magnetic bead and rapid swab RNA extraction methods for detecting rabbit hemorrhagic disease virus 2 in rabbit liver samples
An evaluation of avian influenza virus whole-genome sequencing approaches using nanopore technology
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
Immunogenicity, safety, and anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate in captive black-footed ferrets (Mustela nigripes) and their susceptibility to viral challenge
Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United States
Morbidity and mortality of Hawaiin geese (Branta sandvicensis) and Laysan albatross (Phoebastria immutabilis) associated with reticuloendotheliosis virus
Science and Products
Investigating coronaviruses and white-nose syndrome fungus in free-ranging North American bats
Avian Influenza Surveillance
Tracking Bats and Coronaviruses
Diagnostic Virology Laboratory (DVL)
The USGS National Wildlife Health Center's Diagnostic Virology Laboratory (DVL) detects existing and identifies emerging pathogens of wildlife.
Avian Influenza
Vector-Borne Diseases
Human Influenza Virus Infects Sea Otters
Avian disease screening of translocated sage grouse captured in Montana, USA
Little Brown Bats (Myotis lucifugus) weights and Ct values for SARS-CoV-2 Infection challenge
Epidemiologic and diagnostic data from two red foxes (Vulpes vulpes) and one fisher (Pekania pennanti) with highly pathogenic avian influenza H5N1 submitted to the USGS National Wildlife Health Center in 2022
Raw MinION FASTQ datafiles corresponding to the paper “A comparison of avian influenza virus whole genome sequencing approaches using nanopore technology”
Viral loads, histology, and adverse events in transgenic mice after passive transfer of serum from black-footed ferrets (Mustela nigripes) used to assess the anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate
Data from the article “An opportunistic survey reveals an unexpected coronavirus diversity hotspot in North America”
Data set on reticuloendotheliosis in Hawaiian birds
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
Data from pathology of Lagovirus europaeus GI.2/RHDV2/b (rabbit hemorrhagic disease virus 2) in native North American lagomorphs
Avian Influenza Virus Test Results from Active Surveillance of North American Wild Birds Collected by Department of Interior from 2006-2011
Natural infections with Pigeon Paramyxovirus-1: Pathologic changes in Eurasian collared-doves (Streptopelia decaocto) and rock pigeons (Columba livia) in the USA: Data
USGS National Wildlife Health Center laboratory technician preparing avian samples for avian influenza testing.
USGS National Wildlife Health Center laboratory technician preparing avian samples for avian influenza testing.
Samples awaiting testing in the National Wildlife Health Center Diagnostic Virology Laboratory.
Samples awaiting testing in the National Wildlife Health Center Diagnostic Virology Laboratory.
Genotypic clustering of H5N1 avian Influenza viruses in North America evaluated by ordination analysis
Antibody response of endangered riparian brush rabbits to vaccination against rabbit hemorrhagic disease virus 2
Little brown bats (Myotis lucifugus) are resistant to SARS-CoV-2 infection
Highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b infections in wild terrestrial mammals, United States, 2022
H5N1 highly pathogenic avian influenza clade 2.3.4.4b in wild and domestic birds: Introductions into the United States and reassortments, December 2021–April 2022
Successful detection of Delta and Omicron Variants of SARS-CoV-2 by veterinary diagnostic laboratory participants in an interlaboratory comparison exercise
Comparison of magnetic bead and rapid swab RNA extraction methods for detecting rabbit hemorrhagic disease virus 2 in rabbit liver samples
An evaluation of avian influenza virus whole-genome sequencing approaches using nanopore technology
Experimental infection of Mexican free-tailed bats (Tadarida brasiliensis) with SARS-CoV-2
Immunogenicity, safety, and anti-viral efficacy of a subunit SARS-CoV-2 vaccine candidate in captive black-footed ferrets (Mustela nigripes) and their susceptibility to viral challenge
Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United States
Morbidity and mortality of Hawaiin geese (Branta sandvicensis) and Laysan albatross (Phoebastria immutabilis) associated with reticuloendotheliosis virus
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government