Publications
Below is a list of available Fish Health Program peer reviewed and published science.
Filter Total Items: 323
Comprehensive gene expression profiling following DNA vaccination of rainbow trout against infectious hematopoietic necrosis virus
The DNA vaccine based on the glycoprotein gene of Infectious hematopoietic necrosis virus induces a non-specific anti-viral immune response and long-term specific immunity against IHNV. This study characterized gene expression responses associated with the early anti-viral response. Homozygous rainbow trout were injected intra-muscularly (I.M.) with vector DNA or the IHNV DNA vaccine. Gene express
Authors
Maureen K. Purcell, Krista M. Nichols, James R. Winton, Gael Kurath, Gary H. Thorgaard, Paul Wheeler, John D. Hansen, Russell P. Herwig, Linda K. Park
Immunogenicity and efficacy of three recombinant subunit Pasteurella multocida toxin vaccines against progressive atrophic rhinitis in pigs
Three short fragments of recombinant subunit Pasteurella multocida toxin (rsPMT) were constructed for evaluation as candidate vaccines against progressive atrophic rhinitis (PAR) of swine. PMT-specific antibody secreting cells and evidence of cellular immunity were detected in rsPMT-immunized pigs following authentic PMT challenge or homologous antigen booster. Piglets immunized with rsPMT fragmen
Authors
Chih-Ming Liao, Chienjin Huang, Shih-Ling Hsuan, Zeng-Weng Chen, Wei-Cheng Lee, Cheng-I Liu, James R. Winton, Maw-Sheng Chien
Protective immunity and lack of histopathological damage two years after DNA vaccination against infectious hematopoietic necrosis virus in trout
The DNA vaccine pIHNw-G encodes the glycoprotein of the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV). Vaccine performance in rainbow trout was measured 3, 6, 13, 24, and 25 months after vaccination. At three months all fish vaccinated with 0.1 μg pIHNw-G had detectable neutralizing antibody (NAb) and they were completely protected from lethal IHNV challenge with a relative perce
Authors
Gael Kurath, Kyle A. Garver, Serge Corbeil, Diane G. Elliott, Eric D. Anderson, Scott E. LaPatra
An examination of environmental factors associated with Myxobolus cerebralis infection of wild trout in Pennsylvania
Salmonid whirling disease, caused by the myxosporean parasite Myxobolus cerebralis, was first observed in the United States in 1956 in central Pennsylvania. The parasite was subsequently discovered at several culture facilities throughout the state, and widespread distribution of this parasite via the stocking of subclinically infected brook trout Salvelinus fontinalis, rainbow trout Oncorhynchus
Authors
Adam J. Kaeser, Charlotte Rasmussen, William E. Sharpe
Guide to the identification of fish protozoan and metazoan parasites in stained tissue sections
The identification of protozoan and metazoan parasites is traditionally carried out using a series of classical keys based upon the morphology of the whole organism. However, in stained tissue sections prepared for light microscopy, taxonomic features will be missing, thus making parasite identification difficult. This work highlights the characteristic features of representative parasites in tiss
Authors
D.W. Bruno, B. Nowak, D.G. Elliott
Risk of Myxobolus cerebralis infection to rainbow trout in the Madison River, Montana, USA
Myxobolus cerebralis, the parasite that causes salmonid whirling disease, has had detrimental effects on several salmonid populations in the Intermountain West, including the rainbow trout in the Madison River, Montana, USA. The goal of this study was to examine relationships among characteristics of the environment, Tubifex tubifex (the alternate host) populations, and rainbow trout whirling dise
Authors
R.C. Krueger, B.L. Kerans, E.R. Vincent, C. Rasmussen
Reproductive and early life stages pathology - Histopathology workshop report
Pathology occurring during reproduction and larval development represents an important part of the life cycle of fish, and the diseases that affect eggs and larvae often result in significant losses. However, mortality during this period is frequently ignored or poorly researched as the temptation is to replace the losses rather than investigate the causes. A histopathology workshop organised at t
Authors
D.W. Bruno, B. Nowak, Diane G. Elliott
Fish can get diseases too
Infectious diseases are increasingly recognized as an important component of the ecology of fish in the wild. Many of the viral, bacterial, protozoan and fungal pathogens of fish that were initially discovered in captive fish have their origin among wild populations; however, the impact of disease among these free-ranging stocks has been difficult to study. At the WFRC, combinations of field and l
Authors
J. R. Winton, M. Mesa, G. Kurath, D. Elliot
The glycoprotein genes and gene junctions of the fish rhabdoviruses spring viremia of carp virus and hirame rhabdovirus: Analysis of relationships with other rhabdoviruses
The nucleotide sequences of the glycoprotein genes and all of the internal gene junctions of the fish pathogenic rhabdoviruses spring viremia of carp virus (SVCV) and hirame rhabdovirus (HIRRV) have been determined from cDNA clones generated from viral genomic RNA. The SVCV glycoprotein gene sequence is 1588 nucleotides (nt) long and encodes a 509 amino acid (aa) protein. The HIRRV glycoprotein ge
Authors
H.V. Bjorklund, K.H. Higman, Gael Kurath
The chemical disinfection of trout ponds
The need for knowledge concerning the prevention and control of fish diseases has never been greater than it is in this present era of economy when two fish must be raised in the same water which once supported but one. Fish pathologists have contributed a great deal to our knowledge of fish diseases, but there is still much to be learned, particularly concerning better methods of preventing and e
Authors
F. F. Fish