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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 4047

Constraining the oxygen isotopic composition of nitrate produced by nitrification

Measurements of the stable isotope ratios of nitrogen (15N/14N) and oxygen (18O/16O) in nitrate (NO3–) enable identification of sources, dispersal, and fate of natural and contaminant NO3– in aquatic environments. The 18O/16O of NO3– produced by nitrification is often assumed to reflect the proportional contribution of oxygen atom sources, water, and molecular oxygen, in a 2:1 ratio. Culture and s
Authors
Danielle S. Boshers, Julie Granger, Craig R. Tobias, John K. Böhlke, Richard L. Smith

Improved enrichment factor calculations through principal component analysis: Examples from soils near breccia pipe uranium mines, Arizona, USA

The enrichment factor (EF) is a widely used metric for determining how much the presence of an element in a sampling media has increased relative to average natural abundance because of human activity. Calculation of an EF requires the selection of both a background composition and a reference element, choices that can strongly influence the result of the calculation. Here, it is shown how careful
Authors
Carleton R. Bern, Katherine Walton-Day, David L. Naftz

The dual‐domain porosity apparatus: Characterizing dual porosity at the sediment/water interface

The characterization of pore-space connectivity in porous media at the sediment/water interface is critical to understanding contaminant transport and reactive biogeochemical processes in zones of groundwater and surface-water exchange. Previous in situ studies of dual-domain (i.e., mobile/less-mobile porosity) studies have been limited to solute tracer injections at scales of meters to 100s
Authors
Courtney R. Scruggs, Martin A. Briggs, Frederick D. Day-Lewis, Dale D. Werkema, John W. Lane

Identifying natural and anthropogenic variability of uranium at the well scale, Homestake Superfund site, near Milan, New Mexico, USA

The San Mateo Creek Basin in New Mexico, USA is located within the Grants Mineral Belt-an area with numerous uranium (U) ore deposits, mines, and milling operations. Six monitoring wells set in an alluvial aquifer near the Homestake Mining Co. Superfund site in the lower San Mateo Creek Basin were logged with a suite of borehole geophysical tools including spectral gamma-ray (SGR), vertically prof
Authors
Philip T. Harte, Johanna M. Blake, Jonathan V. Thomas, Kent Becher

Behavioral effects of copper on larval white sturgeon

Early–life stage white sturgeon are sensitive to copper (Cu), with adverse behavioral responses observed during previous studies. The objectives of the present study were to quantify the effects of Cu exposure on white sturgeon swimming and feeding behaviors and determine their time to response. Larval sturgeon (1–2, 28, or 35 d posthatch [dph]) were exposed to Cu (0.5–8 μg/L) for 4 to 14 d. Abnor
Authors
Holly J. Puglis, Robin Calfee, Edward E. Little

Chlorinated byproducts of neonicotinoids and their metabolites: An unrecognized human exposure potential?

We recently reported the initial discovery of neonicotinoid pesticides in drinking water and their potential for transformation through chlorination and alkaline hydrolysis during water treatment. The objectives of this research were: (1) to determine if neonicotinoid metabolites are relevant to drinking water exposure and (2) to identify the products formed from chlorination of neonicotinoids and
Authors
Kathryn L. Klarich Wong, Danielle T. Webb, Matthew R. Nagorzanski, Dana W. Kolpin, Michelle L. Hladik, David M. Cwiertny, Gregory H. LeFevre

Potential toxicity of complex mixtures in surface waters from a nationwide survey of United States streams: Identifying in vitro bioactivities and causative chemicals

While chemical analysis of contaminant mixtures remains an essential component of environmental monitoring, bioactivity-based assessments using in vitro systems increasingly play a role in the detection of biological effects. Historically, in vitro assessments focused on a few biological pathways, e.g., aryl hydrocarbon receptor (AhR) or estrogen receptor (ER) activities. High-throughput screening
Authors
Brett R. Blackwell, Gerald T. Ankley, Paul M. Bradley, Keith A. Houck, Sergei S. Makarov, Alexander V. Medvedev, Joe Swintek, Daniel L. Villeneuve

Mixed-chemical exposure and predicted effects potential in wadeable southeastern USA streams

Complex chemical mixtures have been widely reported in larger streams but relatively little work has been done to characterize them and assess their potential effects in headwaterstreams. In 2014, the United States Geological Survey (USGS) sampled 54 Piedmont streams over ten weeks and measured 475 unique organic compounds using five analytical methods. Maximum and median exposure conditions were
Authors
Paul M. Bradley, Celeste A. Journey, Jason P. Berninger, Daniel T. Button, Jimmy M. Clark, Steven R. Corsi, Laura A. DeCicco, Kristina G. Hopkins, Bradley J. Huffman, Naomi Nakagaki, Julia E. Norman, Lisa H. Nowell, Sharon L. Qi, Peter C. Van Metre, Ian R. Waite

A diverse suite of pharmaceuticals contaminates stream and riparian food webs

A multitude of biologically active pharmaceuticals contaminate surface waters globally, yet their presence in aquatic food webs remain largely unknown. Here, we show that over 60 pharmaceutical compounds can be detected in aquatic invertebrates and riparian spiders in six streams near Melbourne, Australia. Similar concentrations in aquatic invertebrate larvae and riparian predators suggest direct
Authors
Erinn K. Richmond, Emma J. Rosi, David M. Walters, Jerker Fikk, Stephen K. Hamilton, Tomas Brodin, Anna Sundelin, Michael R. Grace

Hydrogeochemical controls on brook trout spawning habitats in a coastal stream

Brook trout (Salvelinus fontinalis) spawn in fall and overwintering egg development can benefit from stable, relatively warm temperatures in groundwater-seepage zones. However, eggs are also sensitive to dissolved oxygen concentration, which may be reduced in discharging groundwater (i.e., seepage). We investigated a 2 km reach of the coastal Quashnet River in Cape Cod, Massachusetts, USA, to rela
Authors
Martin A. Briggs, Judson W. Harvey, Stephen T. Hurley, Donald O. Rosenberry, Timothy D. McCobb, Dale D. Werkema, John W. Lane

Contaminants of emerging concern in the environment: Where we have been and what does the future hold?

In 1962, Rachel Carson’s book Silent Spring alerted the nation to the dangers of manmade chemicals and indiscriminate use of pesticides. DDT was the culprit and its use threatened a variety of wildlife, including the national bird, bald eagles. In 1969, pressured by scientists and the public, the United States banned almost all uses of DDT; however, DDT was just the tip of the chemical iceberg. In
Authors
William A. Battaglin, Dana W. Kolpin, Edward T. Furlong, Susan Glassmeyer, Brett R. Blackwell, Steven Corsi, Michael T. Meyer, Paul M. Bradley

Reconnaissance of mixed organic and inorganic chemicals in private and public supply tapwaters at selected residential and workplace sites in the United States

Safe drinking water at the point-of-use (tapwater, TW) is a United States public health priority. Multiple lines of evidence were used to evaluate potential human health concerns of 482 organics and 19 inorganics in TW from 13 (7 public supply, 6 private well self-supply) home and 12 (public supply) workplace locations in 11 states. Only uranium (61.9 μg L–1, private well) exceeded a National Prim

Authors
Paul M. Bradley, Dana W. Kolpin, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Juliane B. Brown, Mary C. Cardon, Kurt D. Carpenter, Steven R. Corsi, Laura A. DeCicco, Julie E. Dietze, Nicola Evans, Edward T. Furlong, Carrie E. Givens, James L. Gray, Dale W. Griffin, Christopher P. Higgins, Michelle L. Hladik, Luke R. Iwanowicz, Celeste A. Journey, Kathryn Kuivila, Jason R. Masoner, Carrie A. McDonough, Michael T. Meyer, James L. Orlando, Mark J. Strynar, Christopher P. Weis, Vickie S. Wilson