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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 4047

Disease introduction is associated with a phase transition in bighorn sheep demographics

Ecological theory suggests that pathogens are capable of regulating or limiting host population dynamics, and this relationship has been empirically established in several settings. However, although studies of childhood diseases were integral to the development of disease ecology, few studies show population limitation by a disease affecting juveniles. Here, we present empirical evidence that dis
Authors
Kezia Manlove, E. Frances Cassirer, Paul C. Cross, Raina K. Plowright, Peter J. Hudson

Sex differences in contaminant concentrations of fish: a synthesis

Comparison of whole-fish polychlorinated biphenyl (PCB) and total mercury (Hg) concentrations in mature males with those in mature females may provide insights into sex differences in behavior, metabolism, and other physiological processes. In eight species of fish, we observed that males exceeded females in whole-fish PCB concentration by 17 to 43%. Based on results from hypothesis testing, we
Authors
Charles P. Madenjian, Richard R. Rediske, David P. Krabbenhoft, Martin A. Stapanian, Sergei M. Chernyak, James P. O'Keefe

Evaluation of potential mechanisms of atrazine-induced reproductive impairment in fathead minnow (Pimephales promelas) and Japanese medaka (Oryzias latipes)

Atrazine has been implicated in reproductive dysfunction of exposed organisms, and previous studies documented decreased egg production in Japanese medaka (Oryzias latipes) and fathead minnows (Pimephales promelas) during 30-d to 38-d exposures to 0.5 µg/L, 5 µg/L, and 50 µg/L atrazine. The authors evaluated possible mechanisms underlying the reduction in egg production. Gene expression in steroid
Authors
Catherine A. Richter, Diana M. Papoulias, Jeffrey J. Whyte, Donald E. Tillitt

Tumours in white suckers from Lake Michigan tributaries: Pathology and prevalence

The prevalence and histopathology of neoplastic lesions were assessed in white suckerCatostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised
Authors
Vicki S. Blazer, H.L. Walsh, R.P. Braham, C. M. Hahn, P. Mazik, P.B. McIntyre

Chesapeake Bay fish–osprey (Pandion haliaetus) food chain: Evaluation of contaminant exposure and genetic damage

From 2011 to 2013, a large-scale ecotoxicological study was conducted in several Chesapeake Bay (USA) tributaries (Susquehanna River and flats, the Back, Baltimore Harbor/Patapsco Rivers, Anacostia/ middle Potomac, Elizabeth and James Rivers) and Poplar Island as a mid-Bay reference site. Osprey (Pandion haliaetus) diet and the transfer of contaminants from fish to osprey eggs were evaluated. The
Authors
Rebecca S. Lazarus, Barnett A. Rattner, Peter C. McGowan, Robert C. Hale, Natalie K. Karouna-Reiner, Richard A. Erickson, Mary Ann Ottinger

Reservoirs and water management influence fish mercury concentrations in the western United States and Canada

Anthropogenic manipulation of aquatic habitats can profoundly alter mercury (Hg) cycling and bioaccumulation. The impoundment of fluvial systems is among the most common habitat manipulations and is known to increase fish Hg concentrations immediately following impoundment. However, it is not well understood how Hg concentrations differ between reservoirs and lakes at large spatial and temporal sc
Authors
James J. Willacker, Collin A. Eagles-Smith, Michelle A. Lutz, Michael T. Tate, Jesse M. Lepak, Joshua T. Ackerman

Retrospective: Adjusting contaminant concentrations in bird eggs to account for moisture and lipid Loss during their incubation

By the 1960s, research and monitoring efforts on chlorinated pesticide residues in tissues of wildlife were well underway in North America and Europe. Conservationists and natural resource managers were attempting to resolve whether pesticide exposure and accumulated residues were related to population declines in several species of predatory and scavenging birds (e.g., bald eagle Haliaeetus leuco
Authors
Barnett A. Rattner, Stanley N. Wiemeyer, Lawrence J. Blus

A modeling approach to compare ΣPCB concentrations between congener-specific analyses

Changes in analytical methods over time pose problems for assessing long-term trends in environmental contamination by polychlorinated biphenyls (PCBs). Congener-specific analyses vary widely in the number and identity of the 209 distinct PCB chemical configurations (congeners) that are quantified, leading to inconsistencies among summed PCB concentrations (ΣPCB) reported by different studies. Her
Authors
Polly P. Gibson, Marc A. Mills, Johanna M. Kraus, David M. Walters

Microbial pathogens in source and treated waters from drinking water treatment plants in the United States and implications for human health

An occurrence survey was conducted on selected pathogens in source and treated drinking water collected from 25 drinking water treatment plants (DWTPs) in the United States. Water samples were analyzed for the protozoa Giardia and Cryptosporidium (EPA Method 1623); the fungi Aspergillus fumigatus, Aspergillus niger and Aspergillus terreus (quantitative PCR [qPCR]); and the bacteria Legionella pneu
Authors
Dawn N. King, Maura J. Donohue, Stephen J. Vesper, Eric N. Villegas, Michael W. Ware, Megan E. Vogel, Edward Furlong, Dana W. Kolpin, Susan T. Glassmeyer, Stacy Pfaller

Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants

Even though the presence of endocrine disrupting chemicals (EDCs) with thyroid hormone (TH)-like activities in the environment is a major health concern, the methods for their efficient detection and monitoring are still limited. Here we describe a novel cell assay, based on the translocation of a green fluorescent protein (GFP)—tagged chimeric molecule of glucocorticoid receptor (GR) and the thyr
Authors
Diana A. Stavreva, Lyuba Varticovski, Ludmila Levkova, Anuja A. George, Luke Davis, Gianluca Pegoraro, Vicki S. Blazer, Luke R. Iwanowicz, Gordon L. Hager

Concentrations and spatial patterns of organic contaminants in tree swallow (Tachycineta bicolor) eggs at United States and binational Great Lakes Areas of Concern, 2010–2015

Tree swallows, Tachycineta bicolor, were sampled across the Great Lakes basin in 2010 through 2015 to provide a system-wide assessment of current exposure to organic contaminants. The results provide information identified as critical by regulators to assess the “bird or animal deformity or reproductive problems” beneficial use impairment. Eggs were collected from 69 sites across all 5 Great Lakes
Authors
Christine M. Custer, Thomas W. Custer, Paul Dummer, Diana R. Goldberg, J. Christian Franson