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Aromatic fluorine compounds. VII. Replacement of aromatic -Cl and -NO2 groups by -F

January 1, 1956

Replacement of -Cl by -F in aryl chlorides with potassium fluoride has been extended from 2,4-dinitrochlorobenzene to less activated halides by the use of non-aqueous solvents, especially dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Also replacement of -NO2 by -F in substituted nitrobenzenes was studied in DMF. As a direct result of this study, many aromatic fluorine compounds can now be obtained by a relatively simple synthetic route.

Publication Year 1956
Title Aromatic fluorine compounds. VII. Replacement of aromatic -Cl and -NO2 groups by -F
Authors G. C. Finger, C.W. Kruse
Publication Type Article
Publication Subtype Journal Article
Series Title Journal of the American Chemical Society
Index ID 70010563
Record Source USGS Publications Warehouse