Aspergillosis is a respiratory tract infection caused by fungi of the genus Aspergillus, of which A. fumigatus is the primary species responsible for infections in wild birds (Fig. 13.1). Aspergillosis is not contagious (it will not spread from bird to bird), and it may be an acute, rapidly fatal disease or a more chronic disease. Both forms of the disease are commonly seen in free-ranging birds, but the acute form is generally responsible for large-scale mortality events in adult birds and for brooder pneumonia in hatching birds. Aspergillus sp. also produce aflatoxins (see Chapter 37, Mycotoxins), but the significance of those toxins in the ability of the fungus to cause disease in birds is unknown.