Humans have greatly affected the genetic composition of many different organisms during the Anthropocene. Humans cause genetic changes by affecting the direction and magnitude of evolutionary forces that act to create the Earth's biota. In many cases, we expect the outcome of human actions to be extinction and hybridization of existing species, but other outcomes, such as adaptation, also occur. Given the reach of humans throughout the globe, and recent biotechnology advances that make it possible to move individual genes between species or to remove them, it is likely that human influence on the genetic composition of other organisms will become even more widespread as the Anthropocene progresses.