An improved technique for the 2H/1H analysis of urines from diabetic volunteers
The H2-H2O ambient-temperature equilibration technique for the determination of 2H/1H ratios in urinary waters from diabetic subjects provides improved accuracy over the conventional Zn reduction technique. The standard deviation, ~ 1-2???, is at least a factor of three better than that of the Zn reduction technique on urinary waters from diabetic volunteers. Experiments with pure water and solutions containing glucose, urea and albumen indicate that there is no measurable bias in the hydrogen equilibration technique.The H2-H2O ambient-temperature equilibration technique for the determination of 2H/1H ratios in urinary waters from diabetic subjects provides improved accuracy over the conventional Zn reduction technique. The standard deviation, approximately 1-2%, is at least a factor of three better than that of the Zn reduction technique on urinary waters from diabetic volunteers. Experiments with pure water and solutions containing glucose, urea and albumen indicate that there is no measurable bias in the hydrogen equilibration technique.
Citation Information
Publication Year | 1994 |
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Title | An improved technique for the 2H/1H analysis of urines from diabetic volunteers |
DOI | 10.1002/bms.1200230709 |
Authors | T. B. Coplen, I.T. Harper |
Publication Type | Article |
Publication Subtype | Journal Article |
Series Title | Biological Mass Spectrometry |
Index ID | 70017643 |
Record Source | USGS Publications Warehouse |