The Apalachicola River in northwestern Florida is the location of one of four current U.S. Geological Survey National River Quality Assessments. The investigation of the Apalachicola River and flood plain is designed to quantify the organic detritus and nutrient yield to the productive, estuarine Apalachicola Bay. The extensive riverine flood plain is subject to seasonal flooding which transports large quantities of accumulated, decaying leaf litter from the flood plain into the river and ultimately into Apalachicola Bay. The Apalachicola River Quality Assessment has four major objectives; (1) Determine the accumulation of organic substances and trace elements in benthic organisms and fine-grained sediments; (2) Define the distribution of the major tree communities on the flood plain; (3) Assess the role of leaf fall and decomposition on nutrient yield; and (4) Identify and quantify major sources and pathways of nutrients to the river. Extensive emphasis is given to investigation approaches and techniques to facilitate technology transfer to similar wetland ecosystems. (USGS)