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Some metabolic effects of bacterial endotoxins in salmonid fishes

January 1, 1968

Coho salmon (Oncorhynchus kisutch) and rainbow trout (Salmo gairdneri) were highly resistant to endotoxins from both Escherichia coli and Aeromonas salmonicida (a fish pathogen) at 14 and 18 C.This resistance was investigated with liver tryptophan pyrrolase, liver glycogen depletion in vitro, and the arterial blood pressure as indicators. Liver glycogen depletion was accelerated by both endotoxins, but there was no significant cardiovascular response or effect on liver tryptophan pyrrolase activity. Since the cardiovascular effects of histamine were also limited, it was concluded that the metabolic effects of bacterial endotoxins in salmonids are qualitatively different from those of the higher vertebrates.

Publication Year 1968
Title Some metabolic effects of bacterial endotoxins in salmonid fishes
DOI 10.1139/f69-010
Authors Gary Wedemeyer, A. J. Ross, L. Smith
Publication Type Article
Publication Subtype Journal Article
Series Title Journal of the Fisheries Research Board of Canada
Index ID 70161805
Record Source USGS Publications Warehouse