In a 12 week experiment, lake trout (Salvelinus namaycush) were fed diets in which 50% of the nitrogen was provided by one of six preparations of Saccharomyces yeast. Fish fed baker's yeast with disrupted cell walls grew at a rate equal to that of fish fed the control diet and faster than fish fed intact yeast cells. Fish fed a diet containing disrupted yeast cells previously washed in a saline solution did not perform as well. The results of this study indicated that it may be possible to use more than 50% yeast in the diets of salmonid fishes.