Earthquake damage to light-frame wood buildings is a major concern for North America because of the volume of this construction type. In order to estimate wood building damage using synthetic ground motions, we need to verify the ability of synthetically generated ground motions to simulate realistic damage for this structure type. Through a calibrated damage potential indicator, four different synthetic ground motion models are compared with the historically recorded ground motions at corresponding sites. We conclude that damage for sites farther from the fault (>20 km) is under-predicted on average and damage at closer sites is sometimes over-predicted.