Inferring pathogen presence when sample misclassification and partial observation occur
January 23, 2023
This software contains four separate R scripts and one Matlab script that comprise an analysis to estimate the posterior probability of pathogen presence when sample misclassification and partial observations occur. We develop a Bayesian hierarchal framework that accommodates false negative, false positive, and uncertain detections and apply this framework to a case study of the fungal pathogen Pseudogymnoascus destructans (Pd) identified in Texas bats at the invasion front of white-nose syndrome. The software supports a research article submitted to Methods in Ecology and Evolution.
Citation Information
Publication Year | 2023 |
---|---|
Title | Inferring pathogen presence when sample misclassification and partial observation occur |
DOI | 10.5066/P9PDV4LV |
Authors | Graziella V Direnzo, Evan H Grant, Riley O. Mummah, Brittany A. Mosher |
Product Type | Software Release |
Record Source | USGS Asset Identifier Service (AIS) |
USGS Organization | Cooperative Research Units Program |
Related
Inferring pathogen presence when sample misclassification and partial observation occur
Surveillance programmes are essential for detecting emerging pathogens and often rely on molecular methods to make inference about the presence of a target disease agent. However, molecular methods rarely detect target DNA perfectly. For example, molecular pathogen detection methods can result in misclassification (i.e. false positives and false negatives) or partial detection errors (i.e. detecti
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Evan H. Campbell Grant, Riley O. Mummah, Brittany A. Mosher, Jonah Evans, Graziella Vittoria DiRenzo
Related
Inferring pathogen presence when sample misclassification and partial observation occur
Surveillance programmes are essential for detecting emerging pathogens and often rely on molecular methods to make inference about the presence of a target disease agent. However, molecular methods rarely detect target DNA perfectly. For example, molecular pathogen detection methods can result in misclassification (i.e. false positives and false negatives) or partial detection errors (i.e. detecti
Authors
Evan H. Campbell Grant, Riley O. Mummah, Brittany A. Mosher, Jonah Evans, Graziella Vittoria DiRenzo