Tonie Rocke
Tonie Rocke is a Research Epidemiologist at the National Wildlife Health Center.
Science and Products
Filter Total Items: 13
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Filter Total Items: 132
Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging
Monkeypox (MPX) is a re-emerging zoonotic disease that is endemic in Central and West Africa, where it can cause a smallpox-like disease in humans. Despite many epidemiologic and field investigations of MPX, no definitive reservoir species has been identified. Using recombinant viruses expressing the firefly luciferase (luc) gene, we previously demonstrated the suitability of in vivo bioluminescen
Authors
Elizabeth A. Falendysz, Angela M. Londoño-Navas, Carol U. Meteyer, Nicola Pussini, Juan G. Lopera, Jorge E. Osorio, Tonie E. Rocke
Managing prairie dogs by managing plague: a vaccine for the future?
The Black-footed Ferret Recovery Implementation Team Executive Committee is conducting a project to develop,and (hopefully) eventually implement, a plague vaccination program for prairie dogs. The project is a component of the WesternAssociation of Fish and Wildlife Agencies Grasslands Conservation Initiative. An effective, field-worthy vaccine against plaguecould be the biggest breakthrough in re
Authors
Terry B. Johnson, Tonie E. Rocke, Pete Gober, Bill E. Van Pelt, Michael W. Miller, Daniel W. Tripp, Rachel C. Abbott, David L. Bergman
Season and application rates affect vaccine bait consumption by prairie dogs in Colorado and Utah, USA
Plague, a zoonotic disease caused by the bacterium Yersinia pestis, causes high rates of mortality in prairie dogs (Cynomys spp.). An oral vaccine against plague has been developed for prairie dogs along with a palatable bait to deliver vaccine and a biomarker to track bait consumption. We conducted field trials between September 2009 and September 2012 to develop recommendations for bait distribu
Authors
Daniel W. Tripp, Tonie E. Rocke, Sean P. Streich, Nathanael L. Brown, Julia Rodriguez-Ramos Fernandez, Michael W. Miller
A rapid field test for sylvatic plague exposure in wild animals
Plague surveillance is routinely conducted to predict future epizootics in wildlife and exposure risk for humans. The most common surveillance method for sylvatic plague is detection of antibodies to Yersinia pestis F1 capsular antigen in sentinel animals, such as coyotes (Canis latrans). Current serologic tests for Y. pestis, hemagglutination (HA) test and enzyme-linked immunosorbent assay (ELISA
Authors
Rachel C. Abbott, Robert Hudak, Roy Mondesire, Laurie A. Baeten, Robin E. Russell, Tonie E. Rocke
A recombinant raccoon poxvirus vaccine expressing both Yersinia pestis F1 and truncated V antigens protects animals against lethal plague.
In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307-a truncated version of the V protein) provided superior protection against plague challenge compared to individual single antigen constructs. To reduce costs of vaccine production and facilitate implementation o
Authors
Tonie E. Rocke, B Kingstad-Bakke, W Berlier, J.E. Osorio
The innate immune response may be important for surviving plague in wild Gunnison's prairie dogs
Prairie dogs (Cynomys spp.) are highly susceptible to Yersinia pestis, with ≥99% mortality reported from multiple studies of plague epizootics. A colony of Gunnison's prairie dogs (Cynomys gunnisoni) in the Aubrey Valley (AV) of northern Arizona appears to have survived several regional epizootics of plague, whereas nearby colonies have been severely affected by Y. pestis. To examine potential mec
Authors
Joseph D. Busch, Roger Van Andel, Nathan E. Stone, Kacy R. Cobble, Roxanne Nottingham, Judy Lee, Michael VerSteeg, Jeff Corcoran, Jennifer Cordova, William E. Van Pelt, Megan M. Shuey, Jeffrey T. Foster, James M. Schupp, Stephen Beckstrom-Sternberg, James Beckstrom-Sternberg, Paul Keim, Susan Smith, Julia Rodriguez-Ramos, Judy L. Williamson, Tonie E. Rocke, David M. Wagner
Mapping monkeypox transmission risk through time and space in the Congo Basin
Monkeypox is a major public health concern in the Congo Basin area, with changing patterns of human case occurrences reported in recent years. Whether this trend results from better surveillance and detection methods, reduced proportions of vaccinated vs. non-vaccinated human populations, or changing environmental conditions remains unclear. Our objective is to examine potential correlations betwe
Authors
Yoshinori J. Nakazawa, R. Ryan Lash, Darin S. Carroll, Inger K. Damon, Kevin L. Karem, Mary G. Reynolds, Jorge E. Osorio, Tonie E. Rocke, Jean Malekani, Jean-Jacques Muyembe, Pierre Formenty, A. Townsend Peterson
Sylvatic plague vaccine: A new tool for conservation of threatened and endangered species?
Plague, a disease caused by Yersinia pestis introduced into North America about 100 years ago, is devastating to prairie dogs and the highly endangered black-footed ferret. Current attempts to control plague in these species have historically relied on insecticidal dusting of prairie dog burrows to kill the fleas that spread the disease. Although successful in curtailing outbreaks in most instance
Authors
Rachel C. Abbott, Jorge E. Osorio, Christine M. Bunck, Tonie E. Rocke
Sylvatic plague vaccine and management of prairie dogs
Scientists at the USGS National Wildlife Health Center (NWHC), in collaboration with colleagues at the University of Wisconsin (UW), have developed a sylvatic plague vaccine that shows great promise in protecting prairie dogs against plague (Mencher and others, 2004; Rocke and others, 2010). Four species of prairie dogs reside in the United States and Canada, and all are highly susceptible to plag
Authors
Tonie E. Rocke
Plague
Plague offers readers an overview of this highly complex disease caused by the bacteria Yersinia pestis. The history of the disease, as well as information about Yersinia pestis and its transmission by fleas, is described. The section Geographic Distribution presents areas of the world and United States where plague occurs most commonly in rodents and humans. Species Susceptibility describes infec
Authors
Rachel C. Abbott, Tonie E. Rocke
Resistance to plague among black-tailed prairie dog populations
In some rodent species frequently exposed to plague outbreaks caused by Yersinia pestis, resistance to the disease has evolved as a population trait. As a first step in determining if plague resistance has developed in black-tailed prairie dogs (Cynomys ludovicianus), animals captured from colonies in a plague-free region (South Dakota) and two plague-endemic regions (Colorado and Texas) were chal
Authors
Tonie E. Rocke, Judy Williamson, Kacy R. Cobble, Joseph D. Busch, Michael F. Antolin, David M. Wagner
Science and Products
Filter Total Items: 13
No Result Found
Filter Total Items: 132
Evaluation of monkeypox virus infection of prairie dogs (Cynomys ludovicianus) using in vivo bioluminescent imaging
Monkeypox (MPX) is a re-emerging zoonotic disease that is endemic in Central and West Africa, where it can cause a smallpox-like disease in humans. Despite many epidemiologic and field investigations of MPX, no definitive reservoir species has been identified. Using recombinant viruses expressing the firefly luciferase (luc) gene, we previously demonstrated the suitability of in vivo bioluminescen
Authors
Elizabeth A. Falendysz, Angela M. Londoño-Navas, Carol U. Meteyer, Nicola Pussini, Juan G. Lopera, Jorge E. Osorio, Tonie E. Rocke
Managing prairie dogs by managing plague: a vaccine for the future?
The Black-footed Ferret Recovery Implementation Team Executive Committee is conducting a project to develop,and (hopefully) eventually implement, a plague vaccination program for prairie dogs. The project is a component of the WesternAssociation of Fish and Wildlife Agencies Grasslands Conservation Initiative. An effective, field-worthy vaccine against plaguecould be the biggest breakthrough in re
Authors
Terry B. Johnson, Tonie E. Rocke, Pete Gober, Bill E. Van Pelt, Michael W. Miller, Daniel W. Tripp, Rachel C. Abbott, David L. Bergman
Season and application rates affect vaccine bait consumption by prairie dogs in Colorado and Utah, USA
Plague, a zoonotic disease caused by the bacterium Yersinia pestis, causes high rates of mortality in prairie dogs (Cynomys spp.). An oral vaccine against plague has been developed for prairie dogs along with a palatable bait to deliver vaccine and a biomarker to track bait consumption. We conducted field trials between September 2009 and September 2012 to develop recommendations for bait distribu
Authors
Daniel W. Tripp, Tonie E. Rocke, Sean P. Streich, Nathanael L. Brown, Julia Rodriguez-Ramos Fernandez, Michael W. Miller
A rapid field test for sylvatic plague exposure in wild animals
Plague surveillance is routinely conducted to predict future epizootics in wildlife and exposure risk for humans. The most common surveillance method for sylvatic plague is detection of antibodies to Yersinia pestis F1 capsular antigen in sentinel animals, such as coyotes (Canis latrans). Current serologic tests for Y. pestis, hemagglutination (HA) test and enzyme-linked immunosorbent assay (ELISA
Authors
Rachel C. Abbott, Robert Hudak, Roy Mondesire, Laurie A. Baeten, Robin E. Russell, Tonie E. Rocke
A recombinant raccoon poxvirus vaccine expressing both Yersinia pestis F1 and truncated V antigens protects animals against lethal plague.
In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307-a truncated version of the V protein) provided superior protection against plague challenge compared to individual single antigen constructs. To reduce costs of vaccine production and facilitate implementation o
Authors
Tonie E. Rocke, B Kingstad-Bakke, W Berlier, J.E. Osorio
The innate immune response may be important for surviving plague in wild Gunnison's prairie dogs
Prairie dogs (Cynomys spp.) are highly susceptible to Yersinia pestis, with ≥99% mortality reported from multiple studies of plague epizootics. A colony of Gunnison's prairie dogs (Cynomys gunnisoni) in the Aubrey Valley (AV) of northern Arizona appears to have survived several regional epizootics of plague, whereas nearby colonies have been severely affected by Y. pestis. To examine potential mec
Authors
Joseph D. Busch, Roger Van Andel, Nathan E. Stone, Kacy R. Cobble, Roxanne Nottingham, Judy Lee, Michael VerSteeg, Jeff Corcoran, Jennifer Cordova, William E. Van Pelt, Megan M. Shuey, Jeffrey T. Foster, James M. Schupp, Stephen Beckstrom-Sternberg, James Beckstrom-Sternberg, Paul Keim, Susan Smith, Julia Rodriguez-Ramos, Judy L. Williamson, Tonie E. Rocke, David M. Wagner
Mapping monkeypox transmission risk through time and space in the Congo Basin
Monkeypox is a major public health concern in the Congo Basin area, with changing patterns of human case occurrences reported in recent years. Whether this trend results from better surveillance and detection methods, reduced proportions of vaccinated vs. non-vaccinated human populations, or changing environmental conditions remains unclear. Our objective is to examine potential correlations betwe
Authors
Yoshinori J. Nakazawa, R. Ryan Lash, Darin S. Carroll, Inger K. Damon, Kevin L. Karem, Mary G. Reynolds, Jorge E. Osorio, Tonie E. Rocke, Jean Malekani, Jean-Jacques Muyembe, Pierre Formenty, A. Townsend Peterson
Sylvatic plague vaccine: A new tool for conservation of threatened and endangered species?
Plague, a disease caused by Yersinia pestis introduced into North America about 100 years ago, is devastating to prairie dogs and the highly endangered black-footed ferret. Current attempts to control plague in these species have historically relied on insecticidal dusting of prairie dog burrows to kill the fleas that spread the disease. Although successful in curtailing outbreaks in most instance
Authors
Rachel C. Abbott, Jorge E. Osorio, Christine M. Bunck, Tonie E. Rocke
Sylvatic plague vaccine and management of prairie dogs
Scientists at the USGS National Wildlife Health Center (NWHC), in collaboration with colleagues at the University of Wisconsin (UW), have developed a sylvatic plague vaccine that shows great promise in protecting prairie dogs against plague (Mencher and others, 2004; Rocke and others, 2010). Four species of prairie dogs reside in the United States and Canada, and all are highly susceptible to plag
Authors
Tonie E. Rocke
Plague
Plague offers readers an overview of this highly complex disease caused by the bacteria Yersinia pestis. The history of the disease, as well as information about Yersinia pestis and its transmission by fleas, is described. The section Geographic Distribution presents areas of the world and United States where plague occurs most commonly in rodents and humans. Species Susceptibility describes infec
Authors
Rachel C. Abbott, Tonie E. Rocke
Resistance to plague among black-tailed prairie dog populations
In some rodent species frequently exposed to plague outbreaks caused by Yersinia pestis, resistance to the disease has evolved as a population trait. As a first step in determining if plague resistance has developed in black-tailed prairie dogs (Cynomys ludovicianus), animals captured from colonies in a plague-free region (South Dakota) and two plague-endemic regions (Colorado and Texas) were chal
Authors
Tonie E. Rocke, Judy Williamson, Kacy R. Cobble, Joseph D. Busch, Michael F. Antolin, David M. Wagner