Cathy Richter, PhD
Dr. Cathy Richter is a Research Molecular Biologist at the Columbia Environmental Research Center.
Science and Products
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Environmental DNA calibration study interim technical review report December 2014
The Environmental DNA Calibration Study (ECALS) is a multi-year study to improve the understanding and interpretation of the detection of Asian carp DNA in environmental samples (eDNA) used in early detection monitoring. eDNA surveillance programs seek to detect the presence of genetic material (DNA in cells sloughed off in slime, feces, urine, etc.) extracted from water samples; the detection of
Authors
Kelly Baerwaldt, Meredith L. Bartron, Kurt Schilling, Debbie Lee, Edmond Russo, Trudy Estes, Richard Fischer, Beth Fleming, Michael P. Guilfoyle, Jack Killgore, Richard Lance, Edward Perkins, Martin Schultz, David Smith, Jon J. Amberg, Duane Chapman, Mark P. Gaikowski, Katy E. Klymus, Catherine A. Richter
A reply to Iversen et al.'s comment “Monitoring of animal abundance by environmental DNA - An increasingly obscure perspective”
We appreciate the conversation put forward by Iversen et al. (2015) in their response to our article “Quantification of eDNA shedding rates from invasive bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix” in the 2015 environmental DNA special issue of Biological Conservation.We agree with Iversen et al.'s concern about overly optimistic conclusions that could be d
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Quantification of eDNA shedding rates from invasive bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix
Wildlife managers can more easily mitigate the effects of invasive species if action takes place before a population becomes established. Such early detection requires sensitive survey tools that can detect low numbers of individuals. Due to their high sensitivity, environmental DNA (eDNA) surveys hold promise as an early detection method for aquatic invasive species. Quantification of eDNA amount
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Environmental DNA calibration study. Interim technical review report
Invasive aquatic nuisance species pose a major threat to aquatic ecosystems worldwide. Invasive Asian carps, including bighead carp (Hypophthalmichthys nobilis) and silver carp (H. molitrix) have been steadily dispersing upstream through the Mississippi, Illinois, and Des Plaines Rivers since the 1990s. To prevent further movement up the Illinois River into the Chicago Area Waterway System (CAWS,
Authors
K. Baerwaldt, Meredith L. Bartron, K. Schilling, Debbie Lee, Edmond Russo, Trudy Estes, Richard Fischer, Beth Fleming, Michael P. Guilfoyle, K. Jack Kilgore, Richard Lance, Edward Perkins, Martin Schultz, David Smith, Jon J. Amberg, Duane Chapman, Mark P. Gaikowski, Katy E. Klymus, Cathy A. Richter
Methylmercury-induced changes in gene transcription associated with neuroendocrine disruption in largemouth bass (Micropterus salmoides)
Methyl-mercury (MeHg) is a potent neuroendocrine disruptor that impairs reproductive processes in fish. The objectives of this study were to (1) characterize transcriptomic changes induced by MeHg exposure in the female largemouth bass (LMB) hypothalamus under controlled laboratory conditions, (2) investigate the health and reproductive impacts of MeHg exposure on male and female largemouth bass (
Authors
Catherine A. Richter, Christopher J. Martyniuk, Mandy L. Annis, William G. Brumbaugh, Lia C. Chasar, Nancy D. Denslow, Donald E. Tillitt
Atrazine reduces reproduction in Japanese medaka (Oryzias latipes)
Atrazine is an effective broadleaf herbicide and the second most heavily used herbicide in the United States. Effects along the hypothalamus–pituitary–gonad axis in a number of vertebrate taxa have been demonstrated. Seasonally elevated concentrations of atrazine in surface waters may adversely affect fishes, but only a few studies have examined reproductive effects of this chemical. The present s
Authors
Diana M. Papoulias, Donald E. Tillitt, Melaniya G. Talykina, Jeffrey J. Whyte, Catherine A. Richter
Atrazine reduces reproduction in fathead minnow (Pimephales promelas): raw data report
The herbicide, atrazine, routinely is observed in surface and groundwaters, particularly in the “corn belt” region, a high-use area of the United States. Atrazine has demonstrated effects on reproduction in mammals and amphibians, but the characterization of endocrine-related effects in fish has received only limited attention. Peak concentrations of atrazine in surface water of streams from these
Authors
Donald E. Tillitt, Diana M. Papoulias, Jeffrey J. Whyte, Cathy A. Richter
ECALS: Loading studies interim report October 2013
Here we follow up the loading studies interim report from July 2013 and include results
from laboratory studies assessing the effects of diet on eDNA shedding rates by
bigheaded carps(silver and bighead carp). In order to understand how eDNA behavesin
the environment, we must understand how it enters the system. In our July interim
report, we addressed three of our four hypotheses that could i
Authors
Katy Klymus, Cathy Richter, Duane Chapman, Craig P. Paukert
ECALS: Loading studies interim report July 2013
Since the initial detection of Asian carp moving up the Mississippi Basin, the potential for invasion of the Great Lakes by Silver Carp and Bighead Carp has been a major concern to stakeholders. To combat this problem, sampling for environmental DNA (eDNA) is used to monitor the waterways near Lake Michigan. This monitoring area includes the Chicago Area Waterways System (CAWS) and the Des Plaines
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Identification of the thiamin pyrophosphokinase gene in rainbow trout: Characteristic structure and expression of seven splice variants in tissues and cell lines and during embryo development
Thiamin pyrophosphokinase (TPK) converts thiamin to its active form, thiamin diphosphate. In humans, TPK expression is down-regulated in some thiamin deficiency related syndrome, and enhanced during pregnancy. Rainbow trout are also vulnerable to thiamin deficiency in wild life and are useful models for thiamin metabolism research. We identified the tpk gene transcript including seven splice varia
Authors
Shinya Yuge, Catherine A. Richter, Maureen K. Wright-Osment, Diane Nicks, Stephanie K. Saloka, Donald E. Tillitt, Weiming Li
Paenibacillus thiaminolyticus is not the cause of thiamine deficiency impeding lake trout (Salvelinus namaycush) recruitment in the Great Lakes
Thiamine (vitamin B1) deficiency is a global concern affecting wildlife, livestock, and humans. In Great Lakes salmonines, thiamine deficiency causes embryo mortality and is an impediment to restoration of native lake trout (Salvelinus namaycush) stocks. Thiamine deficiency in fish may result from a diet of prey with high levels of thiaminase I. The discoveries that the bacterial species Paenibaci
Authors
Catherine A. Richter, Allison N. Evans, Maureen K. Wright-Osment, James L. Zajicek, Scott A. Heppell, Stephen C. Riley, Charles C. Krueger, Donald E. Tillitt
Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxicant and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. The gene expression profile in adult female zebrafish whole brain induced by acute (96 h) MeHg exposure was investigated. Fish were exposed by i
Authors
Catherine A. Richter, Natàlia Garcia-Reyero, Chris Martyniuk, Iris Knoebl, Marie Pope, Maureen K. Wright-Osment, Nancy D. Denslow, Donald E. Tillitt
Non-USGS Publications**
Taylor, J.A., Richter, C.A., Suzuki, A., Watanabe, H., Iguchi, T., Coser, K.R., Shioda, T., and vom Saal, F.S., 2012, Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells: PLOS ONE, v. 7, no. 10, p. e48311
Taylor, J.A., Richter, C.A., Ruhlen, R.L., and vom Saal, F.S., 2011, Estrogenic environmental chemicals and drugs: Mechanisms for effects on the developing male urogenital system: The Journal of Steroid Biochemistry and Molecular Biology, v. 127, no. 1, p. 83-95
Richter, C.A., Taylor, J.A., Ruhlen, R.L., Welshons, W.V., and vom Saal, F.S., 2007, Estradiol and Bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells: Environmental Health Perspectives, v. 115, no. 6, p. 902-908
vom Saal, F.S., Richter, C.A., Mao, J., and Welshons, W.V., 2005, Commercial animal feed: Variability in estrogenic activity and effects on body weight in mice: Birth Defects Research Part A: Clinical and Molecular Teratology, v. 73, no. 7, p. 474-475
Timms, B.G., Howdeshell, K.L., Barton, L., Bradley, S., Richter, C.A., and vom Saal, F.S., 2005, Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra: Proceedings of the National Academy of Sciences of the United States of America, v. 102, no. 19, p. 7014-7019
Richter, C., Timms, B., and vom Saal, F., 2005, Prostate development: mechanisms for opposite effects of low and high doses of estrogenic chemicals, in Naz, R., ed., Endocrine Disruptors: Effects on Male and Female Reproductive Systems: New York, CRC Press, p. 379-410.
vom Saal, F.S., Richter, C.A., Ruhlen, R.R., Nagel, S.C., Timms, B.G., and Welshons, W.V., 2005, The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A: Birth Defects Research Part A: Clinical and Molecular Teratology, v. 73, no. 3, p. 140-145
vom Saal, F.S., Richter, C.A., Ruhlen, R.R., Nagel, S.C., and Welshons, W.V., 2004, Disruption of laboratory experiments due to leaching of Bisphenol A from polycarbonate cages and bottles and uncontrolled variability in components of animal feed, in National Research Council, ed., The Development of Science-based Guidelines for Laboratory Animal Care: Proceedings of the November 2003 International Workshop: The National Academies Press, p. 65-69.
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
Science and Products
Filter Total Items: 19
No Result Found
Filter Total Items: 44
Environmental DNA calibration study interim technical review report December 2014
The Environmental DNA Calibration Study (ECALS) is a multi-year study to improve the understanding and interpretation of the detection of Asian carp DNA in environmental samples (eDNA) used in early detection monitoring. eDNA surveillance programs seek to detect the presence of genetic material (DNA in cells sloughed off in slime, feces, urine, etc.) extracted from water samples; the detection of
Authors
Kelly Baerwaldt, Meredith L. Bartron, Kurt Schilling, Debbie Lee, Edmond Russo, Trudy Estes, Richard Fischer, Beth Fleming, Michael P. Guilfoyle, Jack Killgore, Richard Lance, Edward Perkins, Martin Schultz, David Smith, Jon J. Amberg, Duane Chapman, Mark P. Gaikowski, Katy E. Klymus, Catherine A. Richter
A reply to Iversen et al.'s comment “Monitoring of animal abundance by environmental DNA - An increasingly obscure perspective”
We appreciate the conversation put forward by Iversen et al. (2015) in their response to our article “Quantification of eDNA shedding rates from invasive bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix” in the 2015 environmental DNA special issue of Biological Conservation.We agree with Iversen et al.'s concern about overly optimistic conclusions that could be d
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Quantification of eDNA shedding rates from invasive bighead carp Hypophthalmichthys nobilis and silver carp Hypophthalmichthys molitrix
Wildlife managers can more easily mitigate the effects of invasive species if action takes place before a population becomes established. Such early detection requires sensitive survey tools that can detect low numbers of individuals. Due to their high sensitivity, environmental DNA (eDNA) surveys hold promise as an early detection method for aquatic invasive species. Quantification of eDNA amount
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Environmental DNA calibration study. Interim technical review report
Invasive aquatic nuisance species pose a major threat to aquatic ecosystems worldwide. Invasive Asian carps, including bighead carp (Hypophthalmichthys nobilis) and silver carp (H. molitrix) have been steadily dispersing upstream through the Mississippi, Illinois, and Des Plaines Rivers since the 1990s. To prevent further movement up the Illinois River into the Chicago Area Waterway System (CAWS,
Authors
K. Baerwaldt, Meredith L. Bartron, K. Schilling, Debbie Lee, Edmond Russo, Trudy Estes, Richard Fischer, Beth Fleming, Michael P. Guilfoyle, K. Jack Kilgore, Richard Lance, Edward Perkins, Martin Schultz, David Smith, Jon J. Amberg, Duane Chapman, Mark P. Gaikowski, Katy E. Klymus, Cathy A. Richter
Methylmercury-induced changes in gene transcription associated with neuroendocrine disruption in largemouth bass (Micropterus salmoides)
Methyl-mercury (MeHg) is a potent neuroendocrine disruptor that impairs reproductive processes in fish. The objectives of this study were to (1) characterize transcriptomic changes induced by MeHg exposure in the female largemouth bass (LMB) hypothalamus under controlled laboratory conditions, (2) investigate the health and reproductive impacts of MeHg exposure on male and female largemouth bass (
Authors
Catherine A. Richter, Christopher J. Martyniuk, Mandy L. Annis, William G. Brumbaugh, Lia C. Chasar, Nancy D. Denslow, Donald E. Tillitt
Atrazine reduces reproduction in Japanese medaka (Oryzias latipes)
Atrazine is an effective broadleaf herbicide and the second most heavily used herbicide in the United States. Effects along the hypothalamus–pituitary–gonad axis in a number of vertebrate taxa have been demonstrated. Seasonally elevated concentrations of atrazine in surface waters may adversely affect fishes, but only a few studies have examined reproductive effects of this chemical. The present s
Authors
Diana M. Papoulias, Donald E. Tillitt, Melaniya G. Talykina, Jeffrey J. Whyte, Catherine A. Richter
Atrazine reduces reproduction in fathead minnow (Pimephales promelas): raw data report
The herbicide, atrazine, routinely is observed in surface and groundwaters, particularly in the “corn belt” region, a high-use area of the United States. Atrazine has demonstrated effects on reproduction in mammals and amphibians, but the characterization of endocrine-related effects in fish has received only limited attention. Peak concentrations of atrazine in surface water of streams from these
Authors
Donald E. Tillitt, Diana M. Papoulias, Jeffrey J. Whyte, Cathy A. Richter
ECALS: Loading studies interim report October 2013
Here we follow up the loading studies interim report from July 2013 and include results
from laboratory studies assessing the effects of diet on eDNA shedding rates by
bigheaded carps(silver and bighead carp). In order to understand how eDNA behavesin
the environment, we must understand how it enters the system. In our July interim
report, we addressed three of our four hypotheses that could i
Authors
Katy Klymus, Cathy Richter, Duane Chapman, Craig P. Paukert
ECALS: Loading studies interim report July 2013
Since the initial detection of Asian carp moving up the Mississippi Basin, the potential for invasion of the Great Lakes by Silver Carp and Bighead Carp has been a major concern to stakeholders. To combat this problem, sampling for environmental DNA (eDNA) is used to monitor the waterways near Lake Michigan. This monitoring area includes the Chicago Area Waterways System (CAWS) and the Des Plaines
Authors
Katy E. Klymus, Cathy A. Richter, Duane Chapman, Craig P. Paukert
Identification of the thiamin pyrophosphokinase gene in rainbow trout: Characteristic structure and expression of seven splice variants in tissues and cell lines and during embryo development
Thiamin pyrophosphokinase (TPK) converts thiamin to its active form, thiamin diphosphate. In humans, TPK expression is down-regulated in some thiamin deficiency related syndrome, and enhanced during pregnancy. Rainbow trout are also vulnerable to thiamin deficiency in wild life and are useful models for thiamin metabolism research. We identified the tpk gene transcript including seven splice varia
Authors
Shinya Yuge, Catherine A. Richter, Maureen K. Wright-Osment, Diane Nicks, Stephanie K. Saloka, Donald E. Tillitt, Weiming Li
Paenibacillus thiaminolyticus is not the cause of thiamine deficiency impeding lake trout (Salvelinus namaycush) recruitment in the Great Lakes
Thiamine (vitamin B1) deficiency is a global concern affecting wildlife, livestock, and humans. In Great Lakes salmonines, thiamine deficiency causes embryo mortality and is an impediment to restoration of native lake trout (Salvelinus namaycush) stocks. Thiamine deficiency in fish may result from a diet of prey with high levels of thiaminase I. The discoveries that the bacterial species Paenibaci
Authors
Catherine A. Richter, Allison N. Evans, Maureen K. Wright-Osment, James L. Zajicek, Scott A. Heppell, Stephen C. Riley, Charles C. Krueger, Donald E. Tillitt
Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxicant and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. The gene expression profile in adult female zebrafish whole brain induced by acute (96 h) MeHg exposure was investigated. Fish were exposed by i
Authors
Catherine A. Richter, Natàlia Garcia-Reyero, Chris Martyniuk, Iris Knoebl, Marie Pope, Maureen K. Wright-Osment, Nancy D. Denslow, Donald E. Tillitt
Non-USGS Publications**
Taylor, J.A., Richter, C.A., Suzuki, A., Watanabe, H., Iguchi, T., Coser, K.R., Shioda, T., and vom Saal, F.S., 2012, Dose-related estrogen effects on gene expression in fetal mouse prostate mesenchymal cells: PLOS ONE, v. 7, no. 10, p. e48311
Taylor, J.A., Richter, C.A., Ruhlen, R.L., and vom Saal, F.S., 2011, Estrogenic environmental chemicals and drugs: Mechanisms for effects on the developing male urogenital system: The Journal of Steroid Biochemistry and Molecular Biology, v. 127, no. 1, p. 83-95
Richter, C.A., Taylor, J.A., Ruhlen, R.L., Welshons, W.V., and vom Saal, F.S., 2007, Estradiol and Bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells: Environmental Health Perspectives, v. 115, no. 6, p. 902-908
vom Saal, F.S., Richter, C.A., Mao, J., and Welshons, W.V., 2005, Commercial animal feed: Variability in estrogenic activity and effects on body weight in mice: Birth Defects Research Part A: Clinical and Molecular Teratology, v. 73, no. 7, p. 474-475
Timms, B.G., Howdeshell, K.L., Barton, L., Bradley, S., Richter, C.A., and vom Saal, F.S., 2005, Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra: Proceedings of the National Academy of Sciences of the United States of America, v. 102, no. 19, p. 7014-7019
Richter, C., Timms, B., and vom Saal, F., 2005, Prostate development: mechanisms for opposite effects of low and high doses of estrogenic chemicals, in Naz, R., ed., Endocrine Disruptors: Effects on Male and Female Reproductive Systems: New York, CRC Press, p. 379-410.
vom Saal, F.S., Richter, C.A., Ruhlen, R.R., Nagel, S.C., Timms, B.G., and Welshons, W.V., 2005, The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A: Birth Defects Research Part A: Clinical and Molecular Teratology, v. 73, no. 3, p. 140-145
vom Saal, F.S., Richter, C.A., Ruhlen, R.R., Nagel, S.C., and Welshons, W.V., 2004, Disruption of laboratory experiments due to leaching of Bisphenol A from polycarbonate cages and bottles and uncontrolled variability in components of animal feed, in National Research Council, ed., The Development of Science-based Guidelines for Laboratory Animal Care: Proceedings of the November 2003 International Workshop: The National Academies Press, p. 65-69.
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.