Dora R Reader (Former Employee)
Science and Products
Publications by this scientist
Filter Total Items: 33
Toxicity to Daphnia pulex and QSAR predictions for polycyclic hydrocarbons representative of Great Lakes contaminants
The objectives of this study were (1) to determine the toxicity of several types of polycyclic hydrocarbons characteristic of Great Lakes samples to Daphnia pulex, a Great Lakes zooplankter, (2) to investigate the influence of different structural characteristics on toxicity, and (3) to determine the linear solvation energy relationship (LSER) parameters and model that describe these compounds. Th
Authors
D.R. Passino-Reader, J.P. Hickey, L.M. Ogilvie
Chronic bioassays of rainbow trout fry with compounds representative of contaminants in Great Lakes fish
To evaluate the hazard of organic compounds detected in Great Lakes fish by gas chromatography/mass spectrometry, we tested compounds representative of heterocyclic nitrogen compounds, polycyclic aromatic hydrocarbons, and cyclic alkanes and alkenes. Sixty-day bioassays on the effects of nicotine, phenanthrene, pinane, and pinene on the behavior, growth, and survival of rainbow trout fry, Oncorhyn
Authors
Dora R. Passino-Reader, William H. Berlin, James P. Hickey
Baseline risk assessment for aquatic life for the Buffalo River, New York, Area of Concern
The Great Lakes National Program Office of the U.S. Environmental Protection Agency initiated the Assessment and Remediation of Contaminated Sediments (ARCS) program to address concerns of environmental degradation at 43 Areas of Concern in the Great Lakes. In our first report (Passino-Reader et al. 1992), we developed a generic approach for baseline hazard evaluation of aquatic life in the Great
Authors
Dora R. Passino-Reader, Patrick L. Hudson, James P. Hickey
An expert system for prediction of chemical toxicity
The National Fisheries Research Center- Great Lakes has developed an interactive computer program that uses the structure of an organic molecule to predict its acute toxicity to four aquatic species. The expert system software, written in the muLISP language, identifies the skeletal structures and substituent groups of an organic molecule from a user-supplied standard chemical notation known as a
Authors
James P. Hickey, Andrew J. Aldridge, Dora R. Passino-Reader, Anthony M. Frank
Linear solvation energy relationships: "rule of thumb" for estimation of variable values
For the linear solvation energy relationship (LSER), values are listed for each of the variables (Vi/100, π*, &betam, αm) for fundamental organic structures and functional groups. We give the guidelines to estimate LSER variable values quickly for a vast array of possible organic compounds such as those found in the environment. The difficulty in generating these variables has greatly discouraged
Authors
James P. Hickey, Dora R. Passino-Reader
An expert system for prediction of aquatic toxicity of contaminants
The National Fisheries Research Center-Great Lakes has developed an interactive computer program in muLISP that runs on an IBM-compatible microcomputer and uses a linear solvation energy relationship (LSER) to predict acute toxicity to four representative aquatic species from the detailed structure of an organic molecule. Using the SMILES formalism for a chemical structure, the expert system ident
Authors
James P. Hickey, Andrew J. Aldridge, Dora R. May Passino, Anthony M. Frank
Linear solvation energy relationships for toxicity of selected organic chemicals to Daphnia pulex and Daphnia magna
In the Laurentian Great Lakes, more than 300 contaminants have been identified in fish, other biota, water, and sediment. Current hazard assessment of these chemicals by the National Fisheries Research Center-Great Lakes is based on their toxicity, occurrence in the environment, and source. Although scientists at the Center have tested over 70 chemicals with the crustacean Daphnia pulex, the numbe
Authors
Dora R. M. Passino, James P. Hickey, Anthony M. Frank
Molecular conductivity indices for modelling toxicities of Great Lakes contaminants to Daphnia pulex
Hazard assessment of hundreds of observed and potential contaminants in fish, sediment, and water of the Great Lakes is necessary to determine impact on fishery sources and other aquatic biota. The hundreds of new compunds introduced each year have few measured properties. Mathematical models based on quantitative structure-activity relationships (QSARs) provide rapid, inexpensive estimates of phy
Authors
James P. Hickey, Dora R. M. Passino, Anthony M. Frank
Acute bioassays and hazard evaluation of representative contaminants detected in Great Lakes fish
We have provided a hazard ranking for 19 classes of compounds representing many of the nearly 500 organic compounds identified by gas chromatography-mass spectrometry in lake trout (Salvelinus namaycush) and walleye (Stizostedion vitreum vitreum) from the Great Lakes and Lake St. Clair. We initially made a provisional hazard ranking based on available published and unpublished information on aquat
Authors
Dora R. May Passino, Stephen B. Smith
Predictive models in hazard assessment of Great Lakes contaminants for fish
A hazard assessment scheme was developed and applied to predict potential harm to aquatic biota of nearly 500 organic compounds detected by gas chromatography/mass spectrometry (GC/MS) in Great Lakes fish. The frequency of occurrence and estimated concentrations of compounds found in lake trout (Salvelinus namaycush) and walleyes (Stizostedion vitreum vitreum) were compared with available manufact
Authors
Dora R. May Passino
Toxicity of toxaphene to Bosmina longirostris and Daphnia spp. (Crustacea)
No abstract available.
Authors
Alexander J. Novak, Dora R. May Passino
Biochemical indicators of stress in fishes: An overview
No abstract available.
Authors
Dora R. M. Passino
Science and Products
Publications by this scientist
Filter Total Items: 33
Toxicity to Daphnia pulex and QSAR predictions for polycyclic hydrocarbons representative of Great Lakes contaminants
The objectives of this study were (1) to determine the toxicity of several types of polycyclic hydrocarbons characteristic of Great Lakes samples to Daphnia pulex, a Great Lakes zooplankter, (2) to investigate the influence of different structural characteristics on toxicity, and (3) to determine the linear solvation energy relationship (LSER) parameters and model that describe these compounds. Th
Authors
D.R. Passino-Reader, J.P. Hickey, L.M. Ogilvie
Chronic bioassays of rainbow trout fry with compounds representative of contaminants in Great Lakes fish
To evaluate the hazard of organic compounds detected in Great Lakes fish by gas chromatography/mass spectrometry, we tested compounds representative of heterocyclic nitrogen compounds, polycyclic aromatic hydrocarbons, and cyclic alkanes and alkenes. Sixty-day bioassays on the effects of nicotine, phenanthrene, pinane, and pinene on the behavior, growth, and survival of rainbow trout fry, Oncorhyn
Authors
Dora R. Passino-Reader, William H. Berlin, James P. Hickey
Baseline risk assessment for aquatic life for the Buffalo River, New York, Area of Concern
The Great Lakes National Program Office of the U.S. Environmental Protection Agency initiated the Assessment and Remediation of Contaminated Sediments (ARCS) program to address concerns of environmental degradation at 43 Areas of Concern in the Great Lakes. In our first report (Passino-Reader et al. 1992), we developed a generic approach for baseline hazard evaluation of aquatic life in the Great
Authors
Dora R. Passino-Reader, Patrick L. Hudson, James P. Hickey
An expert system for prediction of chemical toxicity
The National Fisheries Research Center- Great Lakes has developed an interactive computer program that uses the structure of an organic molecule to predict its acute toxicity to four aquatic species. The expert system software, written in the muLISP language, identifies the skeletal structures and substituent groups of an organic molecule from a user-supplied standard chemical notation known as a
Authors
James P. Hickey, Andrew J. Aldridge, Dora R. Passino-Reader, Anthony M. Frank
Linear solvation energy relationships: "rule of thumb" for estimation of variable values
For the linear solvation energy relationship (LSER), values are listed for each of the variables (Vi/100, π*, &betam, αm) for fundamental organic structures and functional groups. We give the guidelines to estimate LSER variable values quickly for a vast array of possible organic compounds such as those found in the environment. The difficulty in generating these variables has greatly discouraged
Authors
James P. Hickey, Dora R. Passino-Reader
An expert system for prediction of aquatic toxicity of contaminants
The National Fisheries Research Center-Great Lakes has developed an interactive computer program in muLISP that runs on an IBM-compatible microcomputer and uses a linear solvation energy relationship (LSER) to predict acute toxicity to four representative aquatic species from the detailed structure of an organic molecule. Using the SMILES formalism for a chemical structure, the expert system ident
Authors
James P. Hickey, Andrew J. Aldridge, Dora R. May Passino, Anthony M. Frank
Linear solvation energy relationships for toxicity of selected organic chemicals to Daphnia pulex and Daphnia magna
In the Laurentian Great Lakes, more than 300 contaminants have been identified in fish, other biota, water, and sediment. Current hazard assessment of these chemicals by the National Fisheries Research Center-Great Lakes is based on their toxicity, occurrence in the environment, and source. Although scientists at the Center have tested over 70 chemicals with the crustacean Daphnia pulex, the numbe
Authors
Dora R. M. Passino, James P. Hickey, Anthony M. Frank
Molecular conductivity indices for modelling toxicities of Great Lakes contaminants to Daphnia pulex
Hazard assessment of hundreds of observed and potential contaminants in fish, sediment, and water of the Great Lakes is necessary to determine impact on fishery sources and other aquatic biota. The hundreds of new compunds introduced each year have few measured properties. Mathematical models based on quantitative structure-activity relationships (QSARs) provide rapid, inexpensive estimates of phy
Authors
James P. Hickey, Dora R. M. Passino, Anthony M. Frank
Acute bioassays and hazard evaluation of representative contaminants detected in Great Lakes fish
We have provided a hazard ranking for 19 classes of compounds representing many of the nearly 500 organic compounds identified by gas chromatography-mass spectrometry in lake trout (Salvelinus namaycush) and walleye (Stizostedion vitreum vitreum) from the Great Lakes and Lake St. Clair. We initially made a provisional hazard ranking based on available published and unpublished information on aquat
Authors
Dora R. May Passino, Stephen B. Smith
Predictive models in hazard assessment of Great Lakes contaminants for fish
A hazard assessment scheme was developed and applied to predict potential harm to aquatic biota of nearly 500 organic compounds detected by gas chromatography/mass spectrometry (GC/MS) in Great Lakes fish. The frequency of occurrence and estimated concentrations of compounds found in lake trout (Salvelinus namaycush) and walleyes (Stizostedion vitreum vitreum) were compared with available manufact
Authors
Dora R. May Passino
Toxicity of toxaphene to Bosmina longirostris and Daphnia spp. (Crustacea)
No abstract available.
Authors
Alexander J. Novak, Dora R. May Passino
Biochemical indicators of stress in fishes: An overview
No abstract available.
Authors
Dora R. M. Passino