Publications
Below is a list of available Fish Health Program peer reviewed and published science.
Filter Total Items: 323
Viral hemorrhagic septicemia
Viral hemorrhagic septicemia (VHS) is one of the most important viral diseases of finfish worldwide. In the past, VHS was thought to affect mainly rainbow trout Oncorhynchus mykiss reared at freshwater facilities in Western Europe where it was known by various names including Egtved disease and infectious kidney swelling and liver degeneration (Wolf 1988). Today, VHS is known as an important sourc
Authors
William N. Batts, James R. Winton
Alternative barging strategies to improve survival of salmonids transported from Lower Granite Dam: Final report from the 2006-2008 spring/summer Chinook salmon and Steelhead juvenile migrations
In 2011, the final year class of adult salmon Oncorhynchus spp. returned from smolt groups released for a multi-year study to evaluate an alternate release site for transported fish. Smolts were collected and tagged at Lower Granite Dam, transported, and released at the alternate site near Astoria, Oregon (river kilometer 10) or at the traditional release site near Skamania Landing (rkm 225) just
Authors
Tiffani M. Marsh, William D. Muir, Benjamin P. Sandford, Steven G. Smith, Diane G. Elliott
Development of a real-time PCR assay for detection of planktonic red king crab (Paralithodes camtschaticus (Tilesius 1815)) larvae
The Alaskan red king crab (Paralithodes camtschaticus) fishery was once one of the most economically important single-species fisheries in the world, but is currently depressed. This fishery would benefit from improved stock assessment capabilities. Larval crab distribution is patchy temporally and spatially, requiring extensive sampling efforts to locate and track larval dispersal. Large-scale pl
Authors
Pamela C. Jensen, Maureen K. Purcell, J. Frank Morado, Ginny L. Eckert
Genetic analysis of a novel nidovirus from fathead minnows
A bacilliform virus was isolated from diseased fathead minnows (Pimephales promelas). Analysis of the complete genome coding for the polyprotein (pp1ab), spike (S), membrane (M) and nucleocapsid (N) proteins revealed that the virus was most like white bream virus (WBV), another bacilliform virus isolated from white bream (Blicca bjoerkna L.) and the type species of the genus Bafinivirus within the
Authors
William N. Batts, Andrew E. Goodwin, James R. Winton
Restricted growth of U-type infectious haematopoietic necrosis virus (IHNV) in rainbow trout cells may be linked to casein kinase II activity
Previously, we demonstrated that a representative M genogroup type strain of infectious haematopoietic necrosis virus (IHNV) from rainbow trout grows well in rainbow trout‐derived RTG‐2 cells, but a U genogroup type strain from sockeye salmon has restricted growth, associated with reduced genome replication and mRNA transcription. Here, we analysed further the mechanisms for this growth restrictio
Authors
J. W. Park, C. H. Moon, A. Harmache, A. R. Wargo, M. K. Purcell, M. Bremont, Gael Kurath
The skin: The many functions of fish integument
The integument or skin is the envelope that not only separates and protects a fish from its environment, but also provides the means through which most contacts with the outer world are made. It is a large organ and is continuous with the linings of all body openings, and also covers the fins. Fish integument is a multifunctional organ, and its components may serve important roles in protection, c
Authors
Diane G. Elliott
Exxon Valdez oil spill restoration project final report: Prince William Sound Herring disease program (HDP), restoration project 070819
Surveys of pathogens in Pacific herring from 2007 – 2010 indicated that Ichthyophonus, viral hemorrhagic septicemia virus, and erythrocytic necrosis virus are endemic in Prince William Sound and throughout the NE Pacific. Laboratory studies with VHSV indicated that multiple herring stocks are equally susceptible to the resulting disease, Pacific herring shed copious levels of VHSV (as high at 5x10
Authors
Paul Hershberger, Diane G. Elliott, Eveline J. Emmenegger, John D. Hansen, Gael Kurath, James R. Winton, Richard Kocan, Scott LaPatra
Sensing disease and danger: A survey of vertebrate PRRs and their origins
A key facet of the innate immune response lays in its ability to recognize and respond to invading microorganisms and cellular disturbances. Through the use of germ-line encoded PRRs, the innate immune system is capable of detecting invariant pathogen motifs termed pathogen-associated molecular patterns (PAMPS) that are distinct from host encoded proteins or products released from dying cells, whi
Authors
John D. Hansen, Lucia N. Vojtech, Kerry J. Laing
In Vivo fitness associated with high virulence in a vertebrate virus is a complex trait regulated by host entry, replication, and shedding
The relationship between pathogen fitness and virulence is typically examined by quantifying only one or two pathogen fitness traits. More specifically, it is regularly assumed that within-host replication, as a precursor to transmission, is the driving force behind virulence. In reality, many traits contribute to pathogen fitness, and each trait could drive the evolution of virulence in different
Authors
Andrew R. Wargo, Gael Kurath
About viral hemorrhagic septicemia (VHS) virus. Potential threat of Great Lakes VHS virus in Western United States
Viral hemorrhagic septicemia (VHS) is a disease caused by a virus (VHSV). There are different strains of the virus that can infect marine and freshwater fish species, and the different strains may affect species differently. VHSV has recently invaded the Great Lakes, resulting in many large-scale fish die-offs and new regulatory restrictions for aquaculture throughout the region.
Authors
Jerri L Bartholomew, Gael Kurath, Evi Emmenegger
Host specificity and ecology of infectious hematopoietic necrosis virus (IHNV) in Pacific salmonids
Some circumstances IHNV infection can cause acute disease with mortality ranging from 5-90% in host populations. Genetic typing of IHNV field isolates has shown that three major genetic groups of the virus occur in North America. These groups are designated the U, M, and L virus genogroups because they occur in the upper, middle, and lower portions of the geographic range of IHNV in western North
Authors
Gael Kurath, A. Garver, M. K. Purcell, Ma. Penaranda, Rudakova
Quantitative polymerase chain reaction (PCR) for detection of aquatic animal pathogens in a diagnostic laboratory setting
Real-time, or quantitative, polymerase chain reaction (qPCR) is quickly supplanting other molecular methods for detecting the nucleic acids of human and other animal pathogens owing to the speed and robustness of the technology. As the aquatic animal health community moves toward implementing national diagnostic testing schemes, it will need to evaluate how qPCR technology should be employed. This
Authors
Maureen K. Purcell, Rodman G. Getchell, Carol A. McClure, S.E. Weber, Kyle A. Garver