Publications
Below is a list of available Fish Health Program peer reviewed and published science.
Filter Total Items: 323
Interaction of Francisella noatunensis subsp. orientalis with Oreochromis mossambicus bulbus arteriosus cell line
Francisella noatunensis subsp. orientalis (Fno) (syn. F. asiatica) is an emergent warmwater fish pathogen and the causative agent of piscine francisellosis. Although Fno causes septicemia and can live extracellularly in infected tilapia (Oreochromis spp.), the early interaction of Fno with vasculature endothelium is unknown. In the present study, we examined the interaction of wild-type Fno (WT) a
Authors
Esteban Soto, Susan Yun, J. Lewis, Michael T. Kearney, John D. Hansen
Molecular characterization of a novel orthomyxovirus from rainbow and steelhead trout (Oncorhynchus mykiss)
A novel virus, rainbow trout orthomyxovirus (RbtOV), was isolated in 1997 and again in 2000 from commercially-reared rainbow trout (Oncorhynchus mykiss) in Idaho, USA. The virus grew optimally in the CHSE-214 cell line at 15°C producing a diffuse cytopathic effect; however, juvenile rainbow trout exposed to cell culture-grown virus showed no mortality or gross pathology. Electron microscopy of pre
Authors
William N. Batts, Scott E. LaPatra, Ryan Katona, Eric Leis, Terry Fei Fan Ng, Marine S.O. Bruieuc, Rachel Breyta, Maureen K. Purcell, Thomas B. Waltzek, Eric Delwart, James Winton
Detecting Renibacterium salmoninarum in wild brown trout by use of multiple organ samples and diagnostic methods
Renibacterium salmoninarum, the causative agent of salmonid bacterial kidney disease (BKD), is endemic in many wild trout species in northerly regions. The aim of the present study was to determine the optimal R. salmoninarum sampling/testing strategy for wild brown trout (Salmo trutta L.) populations in Iceland. Fish were netted in a lake and multiple organs—kidney, spleen, gills, oesophagus and
Authors
S. Guomundsdottir, Lynn M. Applegate, I.O. Arnason, A. Kristmundsson, Maureen K. Purcell, Diane G. Elliott
Inhibition of an aquatic rhabdovirus demonstrates promise of a broad-spectrum antiviral for use in aquaculture
Many enveloped viruses cause devastating disease in aquaculture, resulting in significant economic impact. LJ001 is a broad-spectrum antiviral compound that inhibits enveloped virus infections by specifically targeting phospholipids in the lipid bilayer via the production of singlet oxygen (1O2). This stabilizes positive curvature and decreases membrane fluidity, which inhibits virus-cell membrane
Authors
Bethany F. Balmer, Rachel L. Powers, Ting-Hu Zhang, Jihye Lee, Frederic Vigant, Benhur Lee, Michael E. Jung, Maureen K. Purcell, Kevin Snekvik, Hector C. Aguilar
Potential distribution of the viral haemorrhagic septicaemia virus in the Great Lakes region
Viral haemorrhagic septicaemia virus (VHSV) genotype IVb has been responsible for large-scale fish mortality events in the Great Lakes of North America. Anticipating the areas of potential VHSV occurrence is key to designing epidemiological surveillance and disease prevention strategies in the Great Lakes basin. We explored the environmental features that could shape the distribution of VHSV, base
Authors
Luis E. Escobar, Gael Kurath, Joaquim Escobar-Dodero, Meggan E. Craft, Nicholas B.D. Phelps
In memoriam - William Toshio (Tosh) Yasutake, 1922-2016
William Toshio (Tosh) Yasutake, 1922-2016 passed away peacefully at home on December 12, 2016, at the age of 94. He is survived by Fumi, his wife of 66 years, as well as four children and six grandchildren. With his death, the fish health community has lost an outstanding scientist as well as a kind, unassuming, and wonderful human being. Tosh was born on June 10, 1922, in Seattle, Washington, to
Authors
Diane G. Elliott, James R. Winton
Herring Disease Program – Herring Disease Program II
No abstract available.
Authors
Paul Hershberger, Maureen K. Purcell
Infectious hematopoietic necrosis virus virological and genetic surveillance 2000–2012
Surveillance records of the acute RNA pathogen of Pacific salmonid fish infectious hematopoietic necrosis virus are combined for the first time to enable landscape-level ecological analyses and modeling. The study area is the freshwater ecosystems of the large Columbia River watershed in the U.S. states of Washington, Oregon, and Idaho, as well as coastal rivers in Washington and Oregon. The study
Authors
Rachel Breyta, Ilana L. Brito, Gael Kurath, Shannon L. LaDeau
Replication and shedding kinetics of infectious hematopoietic necrosis virus in juvenile rainbow trout
Viral replication and shedding are key components of transmission and fitness, the kinetics of which are heavily dependent on virus, host, and environmental factors. To date, no studies have quantified the shedding kinetics of infectious hematopoietic necrosis virus (IHNV) in rainbow trout (Oncorhynchus mykiss), or how they are associated with replication, making it difficult to ascertain the tran
Authors
Andrew R. Wargo, Robert J. Scott, Benjamin Kerr, Gael Kurath
The family Rhabdoviridae: Mono- and bipartite negative-sense RNA viruses with diverse genome organization and common evolutionary origins
The family Rhabdoviridae consists of mostly enveloped, bullet-shaped or bacilliform viruses with a negative-sense, single-stranded RNA genome that infect vertebrates, invertebrates or plants. This ecological diversity is reflected by the diversity and complexity of their genomes. Five canonical structural protein genes are conserved in all rhabdoviruses, but may be overprinted, overlapped or inter
Authors
Ralf G. Dietzgen, Hideki Kondo, Michael M. Goodin, Gael Kurath, Nikos Vasilakis
Susceptibility of ocean- and stream-type Chinook salmon to isolates of the L, U, and M genogroups of infectious hematopoietic necrosis virus (IHNV)
This study examined the susceptibility of Chinook salmon Oncorhynchus tshawytscha to viral strains from the L, U, and M genogroups of infectious hematopoietic necrosis virus (IHNV) present in western North America. The goal of this investigation was to establish a baseline understanding of the susceptibility of ocean- and stream-type Chinook salmon to infection and mortality caused by exposure to
Authors
Daniel Hernandez, Maureen K. Purcell, Carolyn S. Friedman, Gael Kurath
Possibility and challenges of conversion of current virus species names to Linnaean binomials
Botanical, mycological, zoological, and prokaryotic species names follow the Linnaean format, consisting of an italicized Latinized binomen with a capitalized genus name and a lower case species epithet (e.g., Homo sapiens). Virus species names, however, do not follow a uniform format, and, even when binomial, are not Linnaean in style. In this thought exercise, we attempted to convert all current
Authors
Postler Thomas, Anna N. Clawson, Gaya K. Amarasinghe, Christopher F. Basler, Sina Bavari, Maria Benko, Kim R. Blasdell, Thomas Briese, Michael J. Buchmeier, Alexander Bukreyev, Charles H. Calisher, Kartik Chandran, Remi Charrel, Christopher S. Clegg, Peter L. Collins, Juan Carlos De la Torre, Joseph L. DeRisi, Ralf G. Dietzgen, Olga Dolnik, Ralf Durrwald, John M. Dye, Andrew J. Easton, Sebastian Emonet, Pierre Formenty, Ron A. M. Fouchier, Elodie Ghedin, Jean-Paul Gonzalez, Balazs Harrach, Roger Hewson, Masayuki Horie, Daohong Jiang, Gary P. Kobinger, Hideki Kondo, Andrew Kropinski, Mart Krupovic, Gael Kurath, Robert A. Lamb, Eric M. Leroy, Igor S. Lukashevich, Andrea Maisner, Arcady Mushegian, Sergey V. Netesov, Norbert Nowotny, Jean L. Patterson, Susan L. Payne, Janusz T. Paweska, C.J. Peters, Sheli Radoshitzky, Bertus K. Rima, Victor Romanowski, Dennis Rubbenstroth, Sead Sabanadzovic, Helene Sanfacon, Maria Salvato, Martin Schwemmle, Sophie J. Smither, Mark Stenglein, D.M. Stone, Ayato Takada, Robert B. Tesh, Keizo Tomonaga, N. Tordo, Jonathan S. Towner, Nikos Vasilakis, Victor E. Volchkov, Victoria Jensen, Peter J. Walker, Lin-Fa Wang, Arvind Varsani, Anna E. Whitfield, Francisco Murilo Zerbini, Jens H. Kuhn