Publications
Below is a list of available Fish Health Program peer reviewed and published science.
Filter Total Items: 323
Science to support aquatic animal health
Healthy aquatic ecosystems are home to a diversity of plants, invertebrates, fish and wildlife. Aquatic animal populations face unprecedented threats to their health and survival from climate change, water shortages, habitat alteration, invasive species and environmental contaminants. These environmental stressors can directly impact the prevalence and severity of disease in aquatic populations. F
Authors
Maureen K. Purcell, M. Camille Harris
Hepeviruses of fish
Originally reported from California, the cutthroat trout virus (CTV) has now been isolated from eight species of salmonids in North America. Early work focused on the replication and physical characteristics of the small, round virus, but not until 20 years later was it determined to be most closely related to viruses causing hepatitis E in humans or infecting avian and mammalian hosts. The genome
Authors
William N. Batts
Paramyxoviruses of fish
The first fish paramyxovirus was isolated from normal adult Chinook salmon returning to a coastal hatchery in Oregon in the fall of 1982. Subsequently, the virus was isolated from other stocks of adult Chinook salmon and one stock of adult coho salmon in California, Oregon, Washington and Alaska, leading to its designation as the Pacific salmon paramyxovirus (PSPV). The slow-growing virus can be i
Authors
Theodore R. Meyers, William N. Batts
Identification of the major capsid protein of erythrocytic necrosis virus (ENV) and development of quantitative real-time PCR assays for quantification of ENV DNA
Viral erythrocytic necrosis (VEN) is a disease of marine and anadromous fish that is caused by the erythrocytic necrosis virus (ENV), which was recently identified as a novel member of family Iridoviridae by next-generation sequencing. Phylogenetic analysis of the ENV DNA polymerase grouped ENV with other erythrocytic iridoviruses from snakes and lizards. In the present study, we identified the ge
Authors
Maureen K. Purcell, Schuyler Pearman-Gillman, Rachel L. Thompson, Jacob L. Gregg, Lucas M. Hart, James R. Winton, Eveline J. Emmenegger, Paul K. Hershberger
Ichthyophonus parasite phylogeny based on ITS rDNA structure prediction and alignment identifies six clades, with a single dominant marine type
Despite their widespread, global impact in both wild and cultured fishes, little is known of the diversity, transmission patterns, and phylogeography of parasites generally identified as Ichthyophonus. This study constructed a phylogeny based on the structural alignment of internal transcribed spacer (ITS) rDNA sequences to compare Ichthyophonus isolates from fish hosts in the Atlantic and Pacific
Authors
Jacob Gregg, Rachel L. Thompson, Maureen K. Purcell, Carolyn S. Friedman, Paul Hershberger
Taxonomy of the order Mononegavirales: update 2016
In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article pres
Authors
C.L. Afonso, Gael Kurath, 82 Additional Authors
Recommended reporting standards for test accuracy studies of infectious diseases of finfish, amphibians, molluscs and crustaceans: the STRADAS-aquatic checklist
Complete and transparent reporting of key elements of diagnostic accuracy studies for infectious diseases in cultured and wild aquatic animals benefits end-users of these tests, enabling the rational design of surveillance programs, the assessment of test results from clinical cases and comparisons of diagnostic test performance. Based on deficiencies in the Standards for Reporting of Diagnostic A
Authors
Ian A Gardner, Richard J Whittington, Charles G B Caraguel, Paul Hick, Nicholas J G Moody, Serge Corbeil, Kyle A. Garver, Janet V. Warg, Isabelle Arzul, Maureen K. Purcell, Mark St. J. Crane, Thomas B. Waltzek, Niels J Olesen, Alicia Gallardo Lagno
Characterization of infectious dose and lethal dose of two strains of infectious hematopoietic necrosis virus (IHNV)
The ability to infect a host is a key trait of a virus, and differences in infectivity could put one virus at an evolutionary advantage over another. In this study we have quantified the infectivity of two strains of infectious hematopoietic necrosis virus (IHNV) that are known to differ in fitness and virulence. By exposing juvenile rainbow trout (Oncorhynchus mykiss) hosts to a wide range of vir
Authors
Douglas McKenney, Gael Kurath, Andrew Wargo
Potential drivers of virulence evolution in aquaculture
Infectious diseases are economically detrimental to aquaculture, and with continued expansion and intensification of aquaculture, the importance of managing infectious diseases will likely increase in the future. Here, we use evolution of virulence theory, along with examples, to identify aquaculture practices that might lead to the evolution of increased pathogen virulence. We identify eight prac
Authors
David A. Kennedy, Gael Kurath, Ilana L. Brito, Maureen K. Purcell, Andrew F. Read, James R. Winton, Andrew R. Wargo
Survival, movement, and health of hatchery-raised juvenile Lost River suckers within a mesocosm in Upper Klamath Lake, Oregon
The recovery of endangered Lost River suckers (Deltistes luxatus) in Upper Klamath Lake is limited by poor juvenile survival and failure to recruit into the adult population. Poor water quality, degradation of rearing habitat, and toxic levels of microcystin are hypothesized to contribute to low juvenile survival. Studies of wild juvenile suckers are limited in that capture rates are low and compr
Authors
Danielle M. Hereford, Summer M. Burdick, Diane G. Elliott, Amari Dolan-Caret, Carla M. Conway, Alta C. Harris
Increasing virulence, but not infectivity, associated with serially emergent virus strains of a fish rhabdovirus
Surveillance and genetic typing of field isolates of a fish rhabdovirus, infectious hematopoietic necrosis virus (IHNV), has identified four dominant viral genotypes that were involved in serial viral emergence and displacement events in steelhead trout (Oncorhynchus mykiss) in western North America. To investigate drivers of these landscape-scale events, IHNV isolates designated 007, 111, 110, an
Authors
Rachel Breyta, Douglas McKenney, Tarin Tesfaye, Kotaro Ono, Gael Kurath
Atlantic salmon, Salmo salar L. are broadly susceptible to isolates representing the North American genogroups of infectious hematopoietic necrosis virus
Beginning in 1992, three epidemic waves of infectious hematopoietic necrosis, often with high mortality, occurred in farmed Atlantic salmon Salmo salar L. on the west coast of North America. We compared the virulence of eleven strains of infectious hematopoietic necrosis virus (IHNV), representing the U, M and L genogroups, in experimental challenges of juvenile Atlantic salmon in freshwater. All
Authors
Gael Kurath, James R. Winton, Ole B. Dale, Maureen K. Purcell, Knut Falk, Robert D. Busch