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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 3746

Predictive analysis using chemical-gene interaction networks consistent with observed endocrine activity and mutagenicity of U.S. streams

In a recent U.S. Geological Survey/U.S. Environmental Protection Agency study assessing >700 organic compounds in 38 streams, in vitro assays indicated generally low estrogen, androgen, and glucocorticoid receptor activities, but identified 13 surface waters with 17β estradiol equivalent (E2Eq) activities greater than the 1 ng/L level of concern for feminization of male fish. Among the 36 samples
Authors
Jason P. Berninger, David M. DeMarini, Sarah H. Warren, Jane Ellen Simmons, Vickie S. Wilson, Justin M. Conley, Mikayla D. Armstrong, Dana W. Kolpin, Kathryn Kuivila, Timothy J. Reilly, Kristin M. Romanok, Daniel L. Villeneuve, Paul M. Bradley, Luke R. Iwanowicz

Cell-Based metabolomics for untargeted screening and prioritization of vertebrate-active stressors in streams across the United States

The U.S. Geological Survey and the U.S. Environmental Protection Agency have assessed contaminants in 38 streams across the U.S., using an extensive suite of target-chemical analysis methods along with a variety of biological effects tools. Here we report zebrafish liver (ZFL) cell-culture based NMR metabolomic analysis of these split stream samples. We used this untargeted approach to evaluate th
Authors
Timothy W. Collette, Drew R. Ekman, Huajun Zhen, Ha Nguyen, Paul Bradley, Quincy Teng

Effects of organic ligands and background electrolytes on barite dissolution

Barite dissolution rates and features were investigated under conditions that combine a variety of organic ligands with different background electrolyte solutions. The organic ligands included low molecular weight organic compounds (LMWO) that can be produced by halophilic bacteria and are common in natural environments, as well as synthetic chelators that were previously studied in barite dissolu
Authors
Bingjie Ouyang, Devon Renock, Denise Akob

The presence of antibiotic resistance genes in coastal soil and sediment samples from the eastern seaboard of the USA

Infections from antibiotic resistant microorganisms are considered to be one of the greatest global public health challenges that result in huge annual economic losses. While genes that impart resistance to antibiotics (AbR) existed long before the discovery and use of antibiotics, anthropogenic uses of antibiotics in agriculture, domesticated animals, and humans are known to influence the prevale
Authors
Dale W. Griffin, William Benzel, Shawn C. Fisher, Michael J. Focazio, Luke R. Iwanowicz, Keith A. Loftin, Timothy J. Reilly, Daniel Jones

Seasonal and spatial variation in the location and reactivity of a nitrate-contaminated groundwater discharge zone in a lakebed

Groundwater discharge delivering anthropogenic N from surrounding watersheds can impact lake nutrient budgets. However, upgradient groundwater processes and changing dynamics in N biogeochemistry at the groundwater-lake interface are complex and difficult to resolve. In this study, hydrograph variations in a groundwater flow-through lake altered discharge patterns of a wastewater-derived, groun
Authors
Richard L. Smith, Deborah A. Repert, Deborah Stoliker, Douglas B. Kent, Bongkeun Song, Denis R. LeBlanc, Timothy McCobb, John K. Böhlke, Sung Pil Hyun, Hee Sun Moon

Toxicity of aluminum to Ceriodaphnia dubia in low-hardness waters as affected by natural dissolved organic matter

We conducted a series of 7‐d toxicity tests with Ceriodaphnia dubia in dilutions of low‐hardness natural waters, which contained dissolved organic carbon (DOC) concentrations up to 10 mg/L. Stream waters were mixed with well water to achieve 2 target hardness levels (20 and 35 mg/L) and 4 DOC concentrations. Tests with aluminum (Al)‐spiked waters were conducted in a controlled CO2 atmosphere to ma
Authors
John M. Besser, Danielle M. Cleveland, Chris D. Ivey, Laura Blake

Hydraulic tomography: 3D hydraulic conductivity, fracture network, and connectivity in mudstone

We present the first demonstration of hydraulic tomography (HT) to estimate the three-dimensional (3D) hydraulic conductivity (K) distribution of a fractured aquifer at high-resolution field scale (HRFS), including the fracture network and connectivity through it. We invert drawdown data collected from packer-isolated borehole intervals during 42 pumping tests in a wellfield at the former Naval Ai
Authors
Claire R. Tiedeman, Warren Barrash

Biota dose assessment of small rodents sampled near breccia pipe uranium mines in the Grand Canyon watershed

The biotic exposure and uptake of radionuclides and potential health effects due to breccia pipe uranium mining in the Grand Canyon watershed are largely unknown. This paper describes the use of the RESRAD-BIOTA dose model to assess exposure of small rodents (n = 11) sampled at three uranium mine sites in different stages of ore production (active and postproduction). Rodent tissue and soil concen
Authors
Kelsey M. Minter, Timothy Jannik, Jo Ellen Hinck, Danielle M. Cleveland, Walter P. Kubilius, Wendy W. Kuhne

Geochemical factors controlling dissolved elemental mercury and methylmercury formation in Alaskan wetlands of varying trophic status

Transformations of aqueous inorganic divalent mercury (Hg(II)i) to volatile dissolved gaseous mercury (Hg(0)(aq)) and toxic methylmercury (MeHg) governs mercury bioavailability and fate in northern ecosystems. This study quantified concentrations of aqueous mercury species (Hg(II)i, Hg(0)(aq), MeHg) and relevant geochemical constituents in pore waters of eight Alaskan wetlands that differ in troph
Authors
Brett Poulin, Joseph N. Ryan, Michael Tate, David Krabbenhoft, Mark E Hines, Tamar Barkay, Jeffra Schaefer, George R. Aiken

Tracking legacy mercury in the Hackensack River Estuary using mercury stable isotopes

Spatial redistribution of legacy mercury (Hg) contamination in the Hackensack River estuary (New Jersey, USA) was evaluated using mercury stable isotopes. Total Hg varied from 0.06 to 3.8 µg g-1 in sediment from the tidal Hackensack River and from 15 to 154 µg g-1 near historically contaminated sites in upper Berry's Creek, a tributary of the Hackensack River. delta202Hg values for total Hg from
Authors
John R Reinfelder, Sarah E. Janssen

Demonstrating the value of Earth observations—methods, practical applications, and solutions—group on Earth observations side event proceedings

Executive SummaryThe U.S. Geological Survey, the National Oceanic and Atmospheric Administration, the European Association for Remote Sensing Companies, and the European Space Agency in coordination with the GEOValue Community hosted a side event to the Group on Earth Observations Plenary on October 23–24, 2017, in Washington, D.C. The workshop, entitled “Demonstrating the Value of Earth Observati
Authors
Francoise Pearlman, Collin B. Lawrence, Emily J. Pindilli, Denna Geppi, Carl D. Shapiro, Monica Grasso, Jay Pearlman, Jeffery Adkins, Geoff Sawyer, Alessandra Tassa

Use of high-throughput screening results to prioritize chemicals for potential adverse biological effects within a West Virginia Watershed

Organic chemicals from industrial, agricultural, and residential activities can enter surface waters through regulated and unregulated discharges, combined sewer overflows, stormwater runoff, accidental spills, and leaking septic-conveyance systems on a daily basis. The impact of point and nonpoint contaminant sources can result in adverse biological effects for organisms living in or near surface
Authors
Levi D. Rose, Denise Akob, Shea Tuberty, Jeff Colby, Derek Martin, Steven Corsi, Laura DeCicco